Mesonephric Carcinoma of the Ovary: A Report of Two CasesPhilippe Moerman*, Eveline Lurquin and Ignace Vergote
Department of Pathology and Gynecologic Oncology and Leuven Cancer Institute (I.V.), University Hospital Gasthuisberg, Catholic University of Leuven, Leuven,Belgium
- *Corresponding Author:
- Philippe Moerman
Department of Pathology
University Hospital Gasthuisberg
Herestraat 49, B-3000 Leuven, Belgium
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E-mail: [email protected]
Received date: February 09, 2015; Accepted date: March 12, 2015; Published date: March 14, 2015
Citation: Moerman P, Lurquin E, Vergote I (2015) Mesonephric Carcinoma of the Ovary: A Report of Two Cases. J Cytol Histol 6:317. doi: 10.4172/2157-7099.1000317
Copyright: © 2015 Moerman P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Mesonephric carcinomas of the female genital tract are rare tumors, mainly occurring in the cervix and exceptionally in the uterine corpus. There seems to be a paradigm that the only mesonephric neoplasms arising from the upper zone of the Wolffian system are FATWOs. Indeed, no cases of mesonephric carcinoma of the ovary have been reported in the recent literature. Herein, we describe two cases of ovarian carcinoma with histologic features consistent with mesonephric adenocarcinoma. In both cases, the initial diagnosis of well-differentiated endometrioid adenocarcinoma was withdrawn because of other coexistent growth patterns, and the presence of admixed mesonephric-type structures. The mesonephric identity of the tumors was supported immunohistochemically, in particular by their uniform negativity for ER and PR, and strong reactivity for CD10.