alexa Metabolically Healthy Obesity and the Fit/Fat Phenotype
ISSN: 2167-0943

Journal of Metabolic Syndrome
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Review Article

Metabolically Healthy Obesity and the Fit/Fat Phenotype: Associations with Mortality, Subclinical Cardiovascular Disease and Approach to Treatment

Ayesha Farooq1, Sufian Sorathia1, Sameer Shaharyar1,2, Lara Roberson2 and Hamid Feiz1*
1Aventura Hospital and Medical Center, Aventura, USA
2Center for Prevention and Wellness Research, Baptist Health South Florida, Miami, FL 33139, USA
Corresponding Author : Hamid Feiz
Aventura Hospital and Medical Center
Aventura, FL 33180, USA
Tel: +1 305-682-7000
E-mail: [email protected]
Received April 09, 2015; Accepted May 01, 2015; Published May 04, 2015
Citation: Farooq A, Sorathia S,Shaharyar S, Roberson L, Feiz H (2015) Metabolically Healthy Obesity and the Fit/Fat Phenotype: Associations with Mortality, Subclinical Cardiovascular Disease and Approach to Treatment. J Metabolic Synd 4:176. doi:10.4172/2167-0943.1000176
Copyright: © 2015 Ayesha Farooq, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Obesity is a global epidemic affecting over a third of the adult population. Within the obese, subgroups have been identified, including the metabolically healthy obese (MHO) and the fit/fat phenotypes. The MHO phenotype was traditionally thought to have lower cardiovascular risk than the ‘typically obese’, a notion that is being challenged by recent data. Similarly, the emerging fit/fat phenotype is raising questions about the impact of obesity on mortality and cardiovascular risk. The present narrative review provides an overview of these phenotypes and summarizes current evidence and viewpoints regarding the same. The review then incorporates this data into a format that can be utilized by clinicians and researchers to aid clinical decision-making.


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