alexa Metastatic Hepatocellular Carcinoma to the Nasal Cavity: A Case Report and Review of the Literature
ISSN: 1948-5956

Journal of Cancer Science & Therapy
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Case Report

Metastatic Hepatocellular Carcinoma to the Nasal Cavity: A Case Report and Review of the Literature

Chih-Yi Liu1*, Liang-Che Chang2 and Shih-Wei Yang3

1Department of Pathology, Cathay General Hospital, Sijhih, Taipei, Taiwan

2Department of Pathology, Chang Gung Memorial Hospital, Keelung, Taiwan

3Department of Otolaryngology Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan

*Corresponding Author:
Dr. Chih-Yi Liu, MD
Department of Pathology
Cathay General Hospital
Sijhih, Taipei, Taiwan
Add: #2, Lane 59
Chien-Cheng Road
Sijhih City, Taipei County, Taiwan
Tel: 886-2-26482121 ext.3741
Fax: 886-2- 82370777
E-mail: [email protected]

Received date: January 29, 2011; Accepted date: March 02, 2011; Published date: March 09, 2011

Citation: Liu CY, Chang LC, Yang SW (2011) Metastatic Hepatocellular Carcinoma to the Nasal Cavity: A Case Report and Review of the Literature. J Cancer Sci Ther 3: 081-083. doi:10.4172/1948-5956.1000064

Copyright: © 2011 Liu CY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Hepatocellular carcinoma is a common primary hepatic malignancy in the Asian countries. The prognosis of metastatic hepatocellular carcinoma is very poor if left untreated. Despite the rare occurrence, sinonasal metastasis of hepatocellular carcinoma usually implies an advanced disease stage with dismal outcome. Herein we present a case of metastatic hepatocellular carcinoma involving the nasal cavity. This 55-year-old male patient refused standard therapy after the diagnosis of hepatocellular carcinoma. After a palliative excision for the nasal tumor, the patient died of multiple metastatic diseases. A special consideration should be given to such unusual manifestations of extrahepatic metastases. Promptly clinical evaluation and appropriate intervention for symptomatic palliation are necessary for these terminally ill patients.


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