Methotrexate in Rheumatoid Arthritis: Efficacy and Safety
|Bird P*, Griffiths H and Littlejohn G|
|On behalf of the OPAL Research Group|
|Corresponding Author :||Paul Bird
Combined Rheumatology Practice
Suite 4, Level 1, 19 Kensington St.
Kogarah, New South Wales, 2217, Australia
E-mail: [email protected]
|Received December 17, 2013; Accepted March 10, 2014; Published March 17, 2014|
|Citation: Bird P, Griffiths H, Littlejohn G (2014) Methotrexate in Rheumatoid Arthritis: Efficacy and Safety. J Pharmacovigilance 2:127. doi: 10.4172/2329-6887.1000127|
|Copyright: © 2014 Bird P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
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Methotrexate is the mainstay of treatment in rheumatoid arthritis (RA). Used for over 40 years as an anchor treatment in a number of rheumatic diseases, it remains a gold standard of therapy for RA. This review will provide a concise discussion of the efficacy and safety of methotrexate in rheumatic disease, with a focus on Rheumatoid Arthritis.