alexa Microangiopathic Haemolytic Anemia Associated with Bone Marrow Metastasis in a 12 Year Old Child
ISSN: 2572-4916

Journal of Bone Research
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Microangiopathic Haemolytic Anemia Associated with Bone Marrow Metastasis in a 12 Year Old Child

Ruchi Gupta1*, Khaliqur Rahman1, Surabhi1, Manish K Singh1 and Seema Sharma2

1Department of Haematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, U.P. India

2Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, U.P. India

*Corresponding Author:
Ruchi Gupta
Department of Haematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences
Lucknow, U.P, India
Tel: 0522-2495181
E-mail: [email protected]

Received date: June 10, 2016; Accepted date: June 12, 2016; Published date: June 20, 2016

Citation: Gupta R, Rahman K, Surabhi, Singh MK, Sharma S (2016) Microangiopathic Haemolytic Anemia Associated with Bone Marrow Metastasis in a 12 Year Old Child. J Bone Res 4:i101.

Copyright: © 2016 Gupta R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Abstract

A 12 year old female child presented to the emergency department of our institute with complaints of generalized weakness and lethargy for three months and rapidly progressive breathlessness of 15 days duration. There was history of episodes of hematemesis and melena. Examination was notable for presence of tachypnea, tachycardia, severe pallor, mild pedal edema, right sided pleural effusion, mild hepatomegaly and splenomegaly. Investigations revealed elevated serum lactate dehydrogenase levels, 2127 IU/L, unconjugated hyperbilirubinemia, 3.3 mg/dl, haemoglobin 8.3 g/dl, total leucocyte count, 18×109/L, platelet count, 30×109/L, and a reticulocyte count of 23.3%. Peripheral blood smear showed numerous schistocytes, polychromasia, circulating nucleated red blood cells

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