Microbial Transformations of Plant Origin Compounds as a Step in Preparation of Highly Valuable PharmaceuticalsBlaga Mutafova1*, Sava Mutafov1, Pedro Fernandes2 and Strahil Berkov3
- *Corresponding Author:
- Blaga Mutafova
The Stephan Angeloff Institute of Microbiology
Bulgarian Academy of Sciences, Sofia, Bulgaria
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Received date: April 11, 2016; Accepted date: Apr 25, 2016; Published date: May 10, 2016
Citation: Mutafova B, Mutafov S, Fernandes P, Berkov S (2016) Microbial Transformations of Plant Origin Compounds as a Step in Preparation of Highly Valuable Pharmaceuticals. J Drug Metab Toxicol 7:204. doi:10.4172/2157-7609.1000204
Copyright: © 2016 Mutafova B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The aim of the paper is to present microbial transformation reactions as a step in the preparation of drugs or their key intermediates from plant derived compounds. Described are some successful applications of microbial transformation processes for preparation of steroid drugs and/or their important intermediates as well as some microbial transformations of terpenes, alkaloids, flavonoids and poly(phenols) affording derivatives with improved biological activities.