alexa MicroRNA: A Target Candidate to Turn the Tide
ISSN: 2168-9547

Molecular Biology: Open Access
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Review Article

MicroRNA: A Target Candidate to Turn the Tide

Dhilleswara Rao V*

Department of Biotechnology, Bharathidasan University, TN, India

*Corresponding Author:
Dhilleswara Rao V
Department of Biotechnology
Bharathidasan University, TN, India
Tel: +91 8106544565
E-mail: [email protected]

Received date: November 02, 2015;Accepted date: November 11, 2015; Published date: November 18, 2015

Citation: Dhilleswara Rao V (2015) MicroRNA: A Target Candidate to Turn the Tide. Mol Biol 4:145. doi: 10.4172/2168-9547.1000145

Copyright: © 2015 Dhilleswara Rao V. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Understanding the molecular basis of life is at the centre today, the integration of Computer Science, Mathematics and statistics improved the belief in structural and functional genomics. Recently there is an increased interest in function of non-coding RNA transcripts. Non-coding RNAs are small molecules that are not translated into proteins, but these molecules have a pivotal role in almost all molecular and cellular processes. MicroRNA is one of those noncoding RNA molecules that regulate gene expression at posttranslational level. These 18-25 nt length molecules are primary transcribes consist of a secondary hairpin structure. There are 700 miRNAs in the human genome, at least 1-4% of expressed genes; this makes miRNAs as the biggest group of regulators. This review summarizes biogenesis, role of expression profiles in and at various cellular and molecular mechanisms and their applications. More or less, research on non-coding RNA candidates has been done and proved their importance, however, even more to be proved.


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