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ISSN: 2161-1009

Biochemistry & Analytical Biochemistry
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Commentary

MicroRNAs are Emerging as Most Potential Molecular Biomarkers

Sanjay Yadav1*, Abhishek Jauhari1,2, Nishant Singh1, Tanisha Singh1, Ankur Kumar Srivastav1,2, Parul Singh1, AB Pant1 and Devendra Parmar1

1Developmental Toxicology Division, CSIR-Indian Institute of Toxicology Research, Lucknow, Mahatma Gandhi Marg, Lucknow, UP, India

2Academy of Scientific and Innovative Research (AcSIR), India

*Corresponding Author:
Sanjay Yadav
Developmental Toxicology Division
CSIR-Indian Institute of Toxicology Research, Lucknow
Mahatma Gandhi Marg, Lucknow, UP, India
Tel: +91-522-2613357*223
Fax: +91-522- 2628227
E-mail: [email protected], [email protected] es.in

Received Date: May 06, 2015; Accepted Date: June 10, 2015; Published Date: June 12, 2015

Citation: Yadav S, Jauhari A, Singh N, Singh T, Srivastav AK, et al. (2015) MicroRNAs are Emerging as Most Potential Molecular Biomarkers. Biochem Anal Biochem 4:191. doi:10.4172/2161-1009.1000191

Copyright: © 2015 Yadav S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Broadly biomarker word is defined as quantifiable indicator of disease conditions or physiological changes of living organisms. Biomarker field is very old, only few specific biochemical and molecular biomarkers are identified. Discovery of novel and specific biomarkers is still facing several challenges . Based on the methods of quantification, biomarkers can be classified in three types 1) Imaging biomarkers (like X-ray, ultra sound, CT scan, PET, MRI), 2) Biochemical biomarkers (transaminases, bilirubin, alkaline phosphatase, serum creatinine) and 3) Molecular biomarkers. Molecular biomarkers are defined as markers which are measured based on genomic and proteomic approaches. Molecular biomarkers are most recent development in biomarker field, which is still in early developmental stage and needs tremendous amount of research to identify the specific biomarkers which can help in detection of disease before onset of physio; pathological changes or symptoms.

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