alexa MicroRNAs as Essential Components of Non-Coding Genome
ISSN: 2168-9547

Molecular Biology: Open Access
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MicroRNAs as Essential Components of Non-Coding Genome are Emerging Key Players of Oncogenesis

Mustafa Ozen1,2* and Omer Faruk Karatas1,3

1Department of Medical Genetics, Istanbul University Cerrahpasa Medical School, Istanbul, Turkey

2Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA

3Molecular Biology and Genetics Department, Erzurum Technical University, Erzurum, Turkey

Corresponding Author:
Mustafa Ozen
Istanbul University, Cerrahpasa Medical School
Department of Medical Genetics
Fatih, Istanbul, Turkey
Tel: +90 212-414-3000-21304
Fax: +90 212-414-3184
E-mail: [email protected]

Received date: October 01, 2013; Accepted date: October 02, 2013; Published date: October 07, 2013

Citation: Ozen M, Karatas OF (2013) MicroRNAs, as Essential Components of Non-Coding Genome, are Emerging Key Players of Oncogenesis. Mol Biol 2:e112. doi:10.4172/2168-9547.1000e112

Copyright: © 2013 Ozen M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



miRNA expression profiling remains very crucial for understanding the underlying mechanisms of cancer initiation, progression, invasion or metastasis and developing novel and promising therapeutic applications against cancer. Meanwhile, further studies elucidating miRNAs’ mechanisms of action are necessary to
shed light on how miRNAs function in cancer pathogenesis and to overcome the putative challenges like side effects and problems in delivery to their right targets.


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