alexa Microwave Energy: A Potential and Efficient Source of E
e-ISSN:2320-1215 p-ISSN: 2322-0112

Research & Reviews in Pharmacy and Pharmaceutical Sciences
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Research Article

Microwave Energy: A Potential and Efficient Source of Energy in Pharmaceutical Chemistry

Reshma Rani1* and Atul Kumar2*

1National Cancer Institute-CRO, Via Franco Gallini 2, Aviano 3308, Italy

2Knowledge Park III, Greater Noida, Uttar Pradesh 201308, India

*Corresponding Author:
Dr. Reshma Rani
National Cancer Institute-CRO
Via Franco Gallini 2, Aviano 33081, Italy
E-mail: [email protected]
Atul Kumar
Assistant Professor
Amity University Greater Noida
India
Email: [email protected]

Received:06/10/2015 Accepted: 16/11/2015 Published: 22/11/2015

 

Abstract

Biphenyl derivatives have been synthesized in very high yields by nucleophilic addition of various substituted boronic acids on iodine substituted methyl ester derivatives, which can be further used as starting material for bio-relevant organic molecules. Here, in this paper we report a novel, fast, eco-friendly synthesis of biphenyl aromatic compound via insertion of phenyl ring in moisture sensitive substrate by using palladium catalyst under microwave irradiation (MWI).

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