alexa Mineral Salt Composition and Secondary Metabolites of Ocimum gratissimum L., An Anti-hyperglycemic Plant
ISSN: 2329-6836

Natural Products Chemistry & Research
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Research Article

Mineral Salt Composition and Secondary Metabolites of Ocimum gratissimum L., An Anti-hyperglycemic Plant

N’Guessan Bra YF1*, Martin K2, Kiyinlma C3, Rokia S4,5 and Dieneba KB1

1Faculty of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny Cocody Abidjan, 22 BP 747 Abidjan 22, Ivory Coast

2Biochemistry Laboratory and Applied Chemistry (LABIOCA), 03 BP 7021 Ouagadougou 03, University of Ouagadougou, Burkina Faso

3Faculty of Biological Sciences, University of Péléforo Gon Coulibaly, BP 1328 Korhogo, Ivory Coast

4Departement of Traditional Medicine of Bamako, Mali

5Faculty of Pharmaceutical Sciences of Bamako, Mali

*Corresponding Author:
N’Guessan Bra Yvette Fofie
Faculty of Pharmaceutical and Biological Sciences
University of Félix Houphouët Boigny Cocody Abidjan
22 BP 747 Abidjan 22, Ivory Coast
Tel: 22508885387
E-mail: [email protected]

Received Date: June 20, 2016; Accepted Date: July 13, 2016; Published Date: July 18, 2016

Citation: N’Guessan Bra YF, Martin K, Kiyinlma C, Rokia S, Dieneba KB (2016) Mineral Salt Composition and Secondary Metabolites of Ocimum gratissimum L., An Anti-hyperglycemic Plant. Nat Prod Chem Res 4:235. doi:10.4172/2329- 6836.1000235

Copyright: © 2016 N’Guessan Bra YF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Diabetes mellitus affects more and more people in poor areas of developing countries. The search for an adequate treatment and within the reach of the population has moved us to select the leaves of Ocimum gratissimum. Phytochemical screening was carried out on one hand, detecting major groups of secondary metabolites, on infused 10% aqueous and on the other hand minerals salt in point microanalysis dispersive spectrometry. Toxic test was carried out using white mice CF1 type. The phytochemical screening revealed the presence of saponin, sterol and terpenes, alkaloid polyphenols, tannins and flavonoids and especially mucilage. The amounts of total polyphenols and total flavonoids were respectively 11.98 mg EAG/g and 3.99 mg EQ/g of dry extract. The phytochemical screening revealed moisture content of 8.97%, total ash of 8.45%, sulfuric ash of 10.27% and ash insoluble in hydrochloric acid 0.96%. The presence of Cu, Zn, K, Ca and Mg having an important role in glucose metabolism was revealed. The study of acute toxicity showed that the toxic dose could be greater than 3000 mg/kg. Also, the leaves are eaten as human food by some people. The results of the studies indicated that the leaves of Ocimum gratissimum contains minerals and bioactive secondary metabolites that, in combination, may explain their therapeutic uses for treating diabetes mellitus.

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