alexa Mini Review: Potential Role of Hormones in the Tumors o
ISSN: 1747-0862

Journal of Molecular and Genetic Medicine
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Mini Review

Mini Review: Potential Role of Hormones in the Tumors of Neurofibromatosis Type-1

Mauro Geller1,2*, Lisa Oliveira1,2, Karin Soares Cunha3, Spyros Mezitis GE4, Marcia Gonçalves Ribeiro2

1Teresópolis Medical School (UNIFESO) – Rio de Janeiro, Brazil

2Universidade Federal de Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil

3Universidade Federal Fluminense Medical School (UFF), Niterói, Brazil

4Presbyterian Hospital, Weill-Cornell Medical Center, USA

*Corresponding Author:
Mauro Geller
Teresópolis Medical School (UNIFESO)
Universidade Federal do Rio de Janeiro (UFRJ)
Rio de Janeiro, Brazil
Tel: 5521 2641 7000
E-mail: [email protected]

Received date: August 30, 2016; Accepted date: September 22, 2016; Published date: September 26, 2016

Citation: Geller M, Oliveira L, Cunha KS, Spyros Mezitis GE, Ribeiro MG (2016) Mini Review: Potential Role of Hormones in The Tumors of Neurofibromatosis Type-1. J Mol Genet Med 10: 226 doi:10.4172/1747-0862.1000226

Copyright: © 2016 Geller M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited



Neurofibromatosis type 1 is an autosomal dominant neurocutaneous disorder caused by mutations in the NF1 gene, and presents a very broad spectrum of clinical manifestations and severity, including dermal and plexiform neurofibromas. In this mini review we briefly address the findings present in the literature related to hormone receptors within these tumor types.


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