alexa Mir-195: Roadblock for Reprogramming Aged Cells
ISSN: 2168-9431

Single Cell Biology
Open Access

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Mir-195: Roadblock for Reprogramming Aged Cells

Lin Jiang1, and Yigang Wang2*

1Department of Pathology and Laboratory Medicine, Regenerative Medicine Research, University of Cincinnati, Cincinnati, USA

2Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, USA

*Corresponding Author:
Yigang Wang
Director, Regenerative Medicine Research
Professor, Department of Pathology and Laboratory Medicine
University of Cincinnati, 231 Albert Sabin Way
Cincinnati, OH 45267-0529, USA
Tel: 5135585798
E-mail: [email protected]

Received Date: Mar 29, 2017Apr 11, 2017 Accepted Date: Apr 11, 2017 Published Date: Apr 13, 2017

Citation: Jiang L, Wang Y (2017) Mir-195: Roadblock for Reprogramming Aged Cells. Single Cell Biol 6: 159. doi:10.4172/2168-9431.1000159

Copyright: © 2017 Jiang L, et al. This is an open-access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Advanced age remains the greatest known risk factor for human diseases. According to a National Institute on Aging report, it is anticipated that people aged 65 or older will number nearly 1.5 billion by 2050, representing 16% of the world’s population and a dramatic increase in the economic burden of providing care to patients with senile chronic diseases. Recent evidence strongly supports the current hypotheses that age-induced deterioration of tissue stem cells play an important role in initiation of several aging-associated disorders including heart failure, Alzheimer’s disease, and Parkinson’s disease.


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