Modeling Tumor Initiation as Ricci Flow
- *Corresponding Author:
- Robert Skopec
Tel: +421 908220692
E-mail: [email protected]
Received Date: Apr 25, 2016; Accepted Date: May 24, 2016; Published Date: May 26, 2016
Citation: Skopec R (2016) Modeling Tumor Initiation as Ricci Flow. J Mol Biomarkers Diagn 7:279. doi:10.4172/2155-9929.1000279
Copyright: © 2016 Skopec R. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Small variations in magnetic fields can be environmental stresses. For example cell phones, which give off very weak magnetic fields. It is a question, whether these magnetic fields cause brain tumors in cell-phone users. We can model cancer as invasion from social, through psychological to deepest molecular level by Ricci flow. Mechanism of integrated stress response starts with rapid hormone induced changes in receptor conformation which lead to slower modulations of gene transcription. Inhibition of programmed cell death is a major aspect of tumorigenesis (by oncogenic transcription factors NF-kB, STAT3) through upregulation of survival genes. The afferent input from the limbic network conveys purely psychological stress reactions to the HPA axis. Even dominant oncogenes such as v- Src or K-Ras are unable to induce cancer in adult animals without injury. A strong tumor-associated inflammatory response is initiated by the dynamics of Ricci flow collapsing into an injury point that becomes a rounder cellular dysfunction. Tufts biologists show bioelectrical signals control tumors arising from cancer-causing genes; fatty acid involved in process. The have proved, that cancer, bioelectrical signals and the microbiome are connected.