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ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

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Case Report

Modified Atkins Diet and Low Glycemic Index Treatment for Medication-Resistant Epilepsy: Current Trends in Ketogenic Diet

Tomohiro Kumada*, Tomoko Miyajima, Ikuko Hiejima, Fumihito Nozaki, Anri Hayashi and Tatsuya Fujii

Department of Pediatrics, Shiga Medical Center for Children, Shiga, Japan

Corresponding Author:
Dr. Kumada
Department of Pediatrics
Shiga Medical Center for Children, Moriyama, Japan
Tel: +81775826200
Fax: +81775826304
E-mail: [email protected]

Received date: March 13, 2013; Accepted date: June 13, 2013; Published date: June 20, 2013

Citation: Kumada T, Miyajima T, Hiejima I, Nozaki F, Hayashi A, et al. (2013) Modified Atkins Diet and Low Glycemic Index Treatment for Medication-Resistant Epilepsy: Current Trends in Ketogenic Diet. J Neurol Neurophysiol S2:007. doi:10.4172/2155-9562.S2-007

Copyright: © 2013 Kumada T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Compared to the classical ketogenic diet (KD), the modified Atkins diet (MAD) and the low glycemic index
treatment (LGIT) are more liberal and less restrictive diet therapies for the treatment of medication-resistant epilepsy. The MAD was first reported by Kossoff et al. in 2003, and gained global popularity with sufficient evidence in its efficacy reported recently in a controlled study. The LGIT was first reported by Pfeifer et al. in 2005, and its use has also become widespread. We reviewed the efficacy of both diet therapies in the treatment of medication-resistant epilepsy based on the evidence from previous literatures and our own clinical experience. From our experience, the LGIT was more liberal, tolerable, and dietetically balanced than the MAD. To find out which of these diets is most appropriate in different epilepsies and different patients, future controlled comparative studies on the efficacy, tolerability, and dietetic advantages between the MAD and the LGIT are necessary.


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