alexa Molecular Characterization and Phylogenetic Analysis of BZIP Protein in Plants
ISSN: 0974-276X

Journal of Proteomics & Bioinformatics
Open Access

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Research Article

Molecular Characterization and Phylogenetic Analysis of BZIP Protein in Plants

Dhivya Selvaraj1, Arul Loganathan2 and Sathishkumar Ramalingam1*

1Molecular Biology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore -46, India

2Centre for Plant Molecular Biology, Tamilnadu Agriculture University, Coimbatore-46, India

*Corresponding Author:
Dr. Sathishkumar R
Molecular Biology Laboratory
Department of Biotechnology
Bharathiar University
Coimbatore-46, India
E-mail: [email protected]

Received Date: June 12, 2010; Accepted Date: June 29, 2010; Published Date:June 29, 2010

Citation: Selvaraj D, Loganathan A, Sathishkumar R (2010) Molecular Characterization and Phylogenetic Analysis of BZIP Protein in Plants. J Proteomics Bioinform 3: 230-233. doi: 10.4172/jpb.1000144

Copyright: © 2010 Selvaraj D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

BZIP are a class of dimeric sequence specific DNA-binding proteins, is bipartite in structure containing region of enriched basic amino acids which is adjacent to leucine zippers. It is characterized by several leucine residues regularly spaced at seven amino acid intervals, basic region directly contacts with DNA. The leucine zipper mediates heterodimerization and homodimerization of protein monomers through parallel interactions which is unique to eukaryotes. The plant Arabidopsis thaliana genome shows 67 BZIP proteins. We have predicted dimeric properties of alpha helical leucine zipper and coiled coil structure of BZIP proteins in plants. In this analysis the length of leucine zippers, placement of asparagines in the hydrophobic interface and presence of interhelical electrostatic interactions were focused. Phylogenetic tree was also constructed by studying evolutionary relationship of BZIB existing among the plants.

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