Molecular Characterization of Spitz Tumors: An Approach to Improve Disease Diagnosis and Classification
Received Date: Mar 19, 2019 / Accepted Date: Mar 26, 2019 / Published Date: Apr 02, 2019
Spitz neoplasms are relatively uncommon melanocytic lesions characterized by an epithelioid or spindled cell morphology and present more commonly in younger age. They represent a spectrum from benign to malignant lesions which sometime represent a diagnostic conundrum. Recent advances in the genetic characterization of these lesions allow a better classification with consequent improvement in diagnostic accuracy and patient management. This review aims at summarizing our recent understanding of these lesions at the molecular level.
Keywords: Spitz tumor; Spitz nevus; Spitzoid neoplasm; Atypical spitz tumor; Spitzoid melanoma
Citation: Giubellino A, Zhou Y (2019) Molecular Characterization of Spitz Tumors: An Approach to Improve Disease Diagnosis and Classification. J Mol Genet Med 13:417.
Copyright: © 2019 Giubellino A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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