alexa Monitoring the Maintainability of Deep Inspiration Phase with Cine Acquisition in Patients with Left-Sided Breast Carcinoma Receiving Radiotherapy | OMICS International | Abstract
ISSN: 2155-9619

Journal of Nuclear Medicine & Radiation Therapy
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Research Article

Monitoring the Maintainability of Deep Inspiration Phase with Cine Acquisition in Patients with Left-Sided Breast Carcinoma Receiving Radiotherapy

Evren Ozan Göksel1, Öznur Senkesen1, Evrim Tezcanli2*, Melahat Garipagaoglu2, Halil Küçücük1, Meriç Sengoz2 and Isik Aslay3

1Acibadem Kozyatagi Hospital, Department of Radiation Oncology, Istanbul, Turkey

2Acibadem University, Department of Radiation Oncology, Istanbul, Turkey

3Istanbul University, Oncology Institute, Capa Istanbul, Turkey

*Corresponding Author:
Evrim Tezcanli
Acibadem University
Radiation Oncology Department
Acibadem Kozyatagi Hospital, Inonu Cad.
Okur Sok, No:20, Kozyatagi
Istanbul, Turkey
Tel: +90 216 658 84 36
E-mail: [email protected]

Received date January 26, 2013; Accepted date March 26, 2013; Published date March 30, 2013

Citation: Göksel EO, Senkesen Ö, Tezcanli E, Garipagaoglu M, Küçücük H, et al. (2013) Monitoring the Maintainability of Deep Inspiration Phase with Cine Acquisition in Patients with Left-Sided Breast Carcinoma Receiving Radiotherapy. J Nucl Med Radiat Ther 4:141. doi:10.4172/2155-9619.1000141

Copyright: © 2013 Göksel EO, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objectives: This prospective study aimed to investigate whether left-sided breast carcinoma patients could maintain deep inspiration (DI) during radiotherapy in order to reduce exposed heart volume.
Methods: Twenty-one patients with left breast carcinoma receiving adjuvant breast radiotherapy were included in this study. Breath hold time was monitored using the cine acquisition mode (CAM) of a linear accelerator during treatment in every fraction. Simulated kV and treatment field images were compared to determine whether the patient could achieve the same “breath holding level” (BHD). Maintenance of BHD during beam on time was referred as “maintenance of intrafraction breath holding level” (BHM), and chest wall displacement during each treatment was measured in order to verify the BHM. Furthermore, the relation between treatment time and patient compliance was studied.
Results: Sixteen patients were treated according to the deep inspiration breath hold (DIBH) protocol while 5 patients, excluded due to noncompliance, received their treatment without breath control. For the patients treated with DIBH protocol, maximum heart doses without breath control and DI phases were 3044 cGy and 1347 cGy, while mean heart doses were 348 cGy and 239 cGy, respectively. Median BHD and BHM displacements were 0.2 cm (0– 0.86 cm) and 0.07 cm (0–0.31 cm), respectively. BHD differences were <0.4 cm in all but 2 patients. Treatment time did not affect patient compliance.
Conclusions: DI phase was successful in reducing heart dose and 76.2% of the patients were eligible for DIBH. Treatment during moderate DI phase can be used for selected left-sided breast carcinoma patients and CAM could monitor safe execution.

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