alexa Mother to Child HIV Transmission and Its Predictors among HIV-Exposed Infants: A Retrospective Follow-Up Study in Southwest Ethiopia | OMICS International | Abstract
ISSN 2155-6113

Journal of AIDS & Clinical Research
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Research Article

Mother to Child HIV Transmission and Its Predictors among HIV-Exposed Infants: A Retrospective Follow-Up Study in Southwest Ethiopia

Belay Birlie1, Tadele A Diriba1, Kibrealem Sisay1, Abdisa Gurmessa1, Dinberu Seyoum1* and Mulualem Tadesse2,3

1Department of Statistics, College of Natural Sciences, Jimma University, Jimma, Ethiopia

2Department of Medical Laboratory Sciences and Pathology, College of Health Sciences, Jimma University, Jimma, Ethiopia

3Mycobacteriology Research Center, Institute of Biotechnology, Jimma University, Jimma, Ethiopia

*Corresponding Author:
Dinberu Seyoum
Department of Statistics, College of Natural Sciences
Jimma University, Jimma, Ethiopia, P.O.Box 378, Jimma, Ethiopia
Tel: (+251) 911087966
Fax: +251471114484
E-mail: [email protected]; [email protected]

Received date: July 05, 2016; Accepted date: July 22, 2016; Published date: July 29, 2016

Citation: Birlie B, Diriba TA, Sisay K, Gurmessa A, Seyoum D, et al. (2016) Mother to Child HIV Transmission and Its Predictors among HIV-Exposed Infants: A Retrospective Follow-Up Study in Southwest Ethiopia. J AIDS Clin Res 7:605. doi:10.4172/2155-6113.1000605

Copyright: © 2016 Birlie B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Despite the marked progress in coverage of prevention of mother to child HIV transmission (PMTCT) programs, mother to child HIV transmission (MTCT) rate is not well documented in Southwest Ethiopia. A retrospective follow up study was carried at Jimma University Specialized Hospital PMTCT clinic to quantify MTCT rate and its predictors among HIV-exposed infants. Data were extracted from medical records of HIV-infected women and exposed infants between September 2010 and December 2012. Univariate and multivariate logistic regression analyses were carried out to identify potential factors predicting MTCT. A total of 146 infants born to HIV-infected mothers were included in the analysis. Out of 146 infants, 25 (17%, 95% CI: 11%-23.2%) were HIV positive. In the adjusted multivariate logistic regression analysis, mothers being on late AIDS stage (AOR=5.8; 95% CI: 1.6-16.5), absence of maternal PMTCT interventions (AOR=4.9; 95% CI: 1.4-16.5), home delivery (AOR=8.1; 95% CI: 2.1-31.9) and mixed infant feeding (AOR=5.6; 95% CI: 1.4-41.2) were independently associated with MTCT. We documented a high rate of MTCT among exposed infants in Southwest Ethiopia. All pregnant HIV positive mothers should be enrolled in PMTCT programs at earlier stage and exclusive breast feeding should be encouraged so as to decrease MTCT.

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