alexa Mucinous Adenocarcinoma of Minor Salivary Gland: Case Report and Literature Review
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Mucinous Adenocarcinoma of Minor Salivary Gland: Case Report and Literature Review

Karis Barbosa Guimarães1, Bruna Rafaela Martins Dos Santos2, Manuel Antonio Gordón-Núñez2*, Ricardo José De Holanda Vasconcellos1, Lincoln Souza3 and Hébel Cavalcanti Galvão2
1Post-Graduate Program, Surgery and Traumatology Maxillo-Facial, University of Pernambuco, Recife, PE, Brazil
2Post-Graduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil
3University of Campinas - Unicamp, Sao Paulo, SP, Brazil
Corresponding Author : Manuel Antonio Gordón-Núñez
Universidade Federal do Rio Grande do Norte (UFRN)
Av. Senador Salgado Filho, 1787 – Lagoa Nova
Natal, RN, Brazil, Zip Code 59056-000
Tel: (5584)3215-4108
Fax: (5584)3215-4138
E-mail: [email protected]
Received March 27, 2012; Accepted April 11, 2012; Published April 19, 2012
Citation: Guimarães KB, Santos BRMD, Gordón-Núñez MA, Vasconcellos RJDH, Souza L, et al. (2012) Mucinous Adenocarcinoma of Minor Salivary Gland: Case Report and Literature Review. J Clinic Case Reports 2:126. doi:10.4172/2165-7920.1000126
Copyright: © 2012 Guimarães KB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Mucinous adenocarcinoma (MAC) is a glandular tumor characterized by large pools of extracellular mucin. The tumor can arise as a primary tumor of the major salivary glands. However, its occurrence is exceedingly rare and has only recently been recognized. Only few cases in the major salivary glands have been reported. This report is an additional case of MAC with origin in minor salivary gland at the oral floor. Immunohistochemical analysis of the tumor for cytokeratins 7, 8, 10, 13, 14, 18 e 20, vimentin, SMA, CEA, EMA, p53, ki-67 e histochemical analysis for PAS, Alcian blue e mucicarmin was performed. Predominantly, the tumor expressed cytokeratins 7, 18 and 20 that are commonly found in simple epithelia. Therefore, was observed positivity to PAS, Alcian blue and mucicarmin. No other cancer has been detected. The tumor is considered to be a primary mucinous adenocarcinoma, being the twenty-third case in minor salivary gland reported in the literature and the fourth MAC located in the mouth floor.

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