Multicentric Reticulohistiocytosis: A Reason for Erosive Arthritis
- *Corresponding Author:
- Bin Liu
Department of Rheumatology and Immunology
The Affiliated Hospital of Medical College Qingdao University
No. 16 Jiang Su Lu, Shi Nan District
Qingdao City, Shandong Province, 266003, China
E-mail : [email protected]
Received date: June 03, 2014; Accepted date: June 27, 2014; Published date: July 04, 2014
Citation: Yao Y, Wang J, Liu B, Zhang X, Naguwa SM (2014) Multicentric Reticulohistiocytosis: A Reason for Erosive Arthritis. J Diabetes Metab 5:400. doi:10.4172/2155-6156.1000400
Copyright: © 2014 Yao Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original author and source are credited.
Multicentric Reticulohistiocytosis (MRH) is a rare histiocytic disorder that primarily involves the skin and joints but can affect multiple visceral organs. A female patient presented a characteristic papulonodular skin eruption and polyarthritis with positive Antinuclear Antibody (ANA), and skin biopsy findings demonstrated classic features of MRH. The patient’s clinical manifestations were in remission after treatment, yet X-ray showed progressive erosions of finger joints. MRH is an aggressive, debilitating and disabling condition, an optimal treatment strategy is necessary performed to improve outcome.