alexa Multifunctional Magnetic Bead-Based Dynamic Light Scatt
ISSN: 2155-9821

Journal of Bioprocessing & Biotechniques
Open Access

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Multifunctional Magnetic Bead-Based Dynamic Light Scattering Aptasensor with Rapid and Feasible Determination of Disease-Related Biomarkers

Ying Tang1, Jin Zhang1 and Dianping Tang2*

1Department of Chemistry and Chemical Engineering, Chongqing Key Laboratory of Environmental Materials and Remediation Technologies, Chongqing University of Arts and Sciences, Chongqing, PR China

2Department of Chemistry, MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, PR China

*Corresponding Author:
Dianping Tang
Department of Chemistry, MOE Key Laboratory of Analysis and Detection for Food Safety
Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety
Fuzhou University, Fuzhou-350116, PR China
Tel: +059122866125
E-mail: [email protected]

Received Date: October 14, 2016; Accepted Date: November 08, 2016; Published Date: November 10, 2016

Citation: Tang Y, Zhang J, Tang D (2016) Multifunctional Magnetic Bead-Based Dynamic Light Scattering Aptasensor with Rapid and Feasible Determination of Disease-Related Biomarkers. J Bioprocess Biotech 6:287. doi:10.4172/2155-9821.1000287

Copyright: © 2016 Tang Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

A simple and feasible sensing strategy based on target-induced aggregation of aptasensor-conjugated multifunctional magnetic beads was designed for sensitive detection of low-abundant proteins (carcinoembryonic antigen, CEA, used as an example), coupling with dynamic light scattering technique.

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