alexa Multiple Myeloma Associated Intestinal Amyloidosis: Int
ISSN: 2329-8790

Journal of Hematology & Thromboembolic Diseases
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Research Article

Multiple Myeloma Associated Intestinal Amyloidosis: Intestinal Pseudo- Obstruction Falsely Considered as an Ascites

Vladimir Milivojevic1*, Ješić Vukićević Rada1, Rankovic Ivan2, Stojanovic Maja1,4, Micev Marjan3, Milosavljevic Tomica4

1Department of Clinic for gastroenterology and hepatology, Clinical Center of Serbia, Serbia

2Department of Clinic for allergology and immunology, Clinical Center of Serbia

3School of Medicine, University of Belgrade, Serbia

4Department of pathohistology, Clinical Center of Serbia

*Corresponding Author:
Dr Vladimir Milivojevic
Department of Clinic for gastroenterology and hepatology
Clinical Center of Serbia, Serbia
Tel: +00381638487330
Fax: 003813662361
E-mail: [email protected]

Received date: January 17, 2017; Accepted date: January 17, 2017 Published date: July 7, 2017

Citation: Milivojevic V, Rada JV, Ivan R, Maja S, Marjan S, et al., (2017) Multiple Myeloma Associated Intestinal Amyloidosis: Intestinal Pseudo-Obstruction Falsely Considered as an Ascites. J Hematol Thrombo Dis 6:271. doi: 10.4172/2329-8790.1000271

Copyright: © 2017 Milivojevic V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Aim of our case report is to present a patient with light chain amyloidosis associated with multiple myeloma and intestinal pseudoobstruciton clinically mimicking ascites. Our patient was a 44-year old woman who was admitted to our hospital due to nausea, vomiting, epigastric pain, significant weight loss, diarrhea, abdominal distension and bloating. She had a medical history of end-stage renal disease on haemodialysis and previous chronic viral C hepatitis. She addressed to our hospital after last outpatient ultrasound examination which revealed suspicious free abdominal fluid. After the clinical examination and diagnostic procedures we established diagnosis of multiple myeloma with bowel amyloid deposition and intestinal pseudo-obstruction. On the other side we noticed hepatomegaly and silent liver function tests. Liver biopsy could yielded the possible cause of hepatomegaly, but patient non-compliance hindered the answer is liver involvement consequence of HCV infection or liver amyloidal cumulation. Unfortunately, in further course the patient died before starting specific treatment. Patients with multiple myeloma and obscure abdominal complaints should be worked up for amyloidosis. Intestinal pseudo-obstruction due to amyloidosis can in some hand imitate ascites and hence complicating diagnostic algorithm. In this complicated case is necessary close cooperation between surgeon, gastroenterologist, hepatologist and hematologist.

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