Multiple Myeloma Relapsed with Skull Involvement in Plasmacytoma
- *Corresponding Author:
- Yusuf Kayar
Department of Internal Medicine
Bezmialem Vakıf University
Tel: +90 212 453 1700
E-mail: [email protected]
Received date: July 29, 2016; Accepted date: August 03, 2016; Published date: August 05, 2016
Citation: Kayar Y, Kayar NB, Ekinci I, Coban G, Unver N (2016) Multiple Myeloma Relapsed with Skull Involvement in Plasmacytoma. J Carciong Mutagen 7:273. doi:10.4172/2157-2518.1000273
Copyright: © 2016 Kayar Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Extra medullary plasmacytomas occurring as solitary (primary) tumours or secondary manifestations of multiple myeloma most often involve the upper airways and paranasal sinuses. The skull is one of the rarest sites of extra medullary plasmacytoma. Myelomatous deposits in dural reflections distant from the bony skull, i.e. tentorium and falx, are rarer, and probably result from dissection along layers of meninges. Osseous and pachymeningeal masses in the cranial vault or in the skull base may result in tumefaction, pain, headache, single or multiple cranial nerve palsies or seizure. A case of multiple myeloma relapsed with extra medullary plasmacytoma in the skull; forehead and ear involvement is reported.