alexa Multiple Myeloma Relapsed with Skull Involvement in Pla
ISSN: 2157-2518

Journal of Carcinogenesis & Mutagenesis
Open Access

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Case Report

Multiple Myeloma Relapsed with Skull Involvement in Plasmacytoma

Yusuf Kayar1*, Nuket Bayram Kayar2, Iskender Ekinci1, Ganime Coban3 and Nurcan Unver3

1Department of Internal Medicine, Bezmialem Vakıf University, Istanbul, Turkey

2Department of Family Medicine, Bagcilar Education and Research Hospital, Istanbul, Turkey

3Department of Pathology, Bezmialem Vakıf University, Istanbul, Turkey

*Corresponding Author:
Yusuf Kayar
Department of Internal Medicine
Bezmialem Vakıf University
Istanbul, Turkey
Tel: +90 212 453 1700
E-mail: [email protected]

Received date: July 29, 2016; Accepted date: August 03, 2016; Published date: August 05, 2016

Citation: Kayar Y, Kayar NB, Ekinci I, Coban G, Unver N (2016) Multiple Myeloma Relapsed with Skull Involvement in Plasmacytoma. J Carciong Mutagen 7:273. doi:10.4172/2157-2518.1000273

Copyright: © 2016 Kayar Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Extra medullary plasmacytomas occurring as solitary (primary) tumours or secondary manifestations of multiple myeloma most often involve the upper airways and paranasal sinuses. The skull is one of the rarest sites of extra medullary plasmacytoma. Myelomatous deposits in dural reflections distant from the bony skull, i.e. tentorium and falx, are rarer, and probably result from dissection along layers of meninges. Osseous and pachymeningeal masses in the cranial vault or in the skull base may result in tumefaction, pain, headache, single or multiple cranial nerve palsies or seizure. A case of multiple myeloma relapsed with extra medullary plasmacytoma in the skull; forehead and ear involvement is reported.


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