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MU-Tomo: Independent Dose Validation Software for Helical TomoTherapy | OMICS International | Abstract
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

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Research Article

MU-Tomo: Independent Dose Validation Software for Helical TomoTherapy

Nikos Papanikolaou1*, Weihong He1, Luis A Vazquez Q1, Alonso Gutierrez1, Sotirios Stathakis1, Hassaan Alkhatib2 and Chengyu Shi1

1Cancer Therapy and Research Center, Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, TX, USA

2South Carolina Radiation Oncology Associates, Columbia, SC, USA

*Corresponding Author:
Dr. Nikos Papanikolaou, PhD
Cancer Therapy and Research Center
Department of Radiation Oncology
7979 Wurzbach Rd Ste 240
University of Texas Health Science Center at San Antonio
Tel: 210-450- 1028
Fax: 210-450-1076
E-mail: [email protected]

Received Date: July 29, 2010; Accepted Date: September 07, 2010; Published Date: September 07, 2010

Citation: Papanikolaou N, He W, Vazquez LA, Gutierrez A, Stathakis S, et al. (2010) MU-Tomo: Independent Dose Validation Software for Helical TomoTherapy. J Cancer Sci Ther 2: 145-152. doi:10.4172/1948-5956.1000040

Copyright: © 2010 Papanikolaou N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


A software program, MU-Tomo, has been developed to perform an independent point dose calculation and compare it to the dose calculated from the TomoTherapy (TomoTherapy, Inc., Madison, WI) treatment planning system (TPS). Input parameters required for this software include: archived tomotherapy patient files, QA plan image coordinates, tomotherapy-calculated point dose and machine-specific dosimetric parameters such as the off-axis ratios (OARx and OARy), tissue phantom ratios (TPR) and output functions (Scp). The software was validated on four phantom models and fifty tomotherapy patient plans representing various anatomical sites. Our results indicate that MU-Tomo can perform in a few seconds an independent dose calculation accurately and provide a secondary check for a point dose validation of helical tomotherapy plans.


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