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Nano-Lactoferrin in Diagnostic, Imaging and Targeted Delivery for Cancer and Infectious Diseases | OMICS International | Abstract
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

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Review Article

Nano-Lactoferrin in Diagnostic, Imaging and Targeted Delivery for Cancer and Infectious Diseases

Jagat R. Kanwar1*, Rasika M. Samarasinghe1, Rakesh Sehgal2 and Rupinder K. Kanwar1

1Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (LIMBR), Centre for Biotechnology and Interdisciplinary Biosciences (BioDeakin), Institute for Technology & Research Innovation (ITRI), Deakin University, Geelong, Technology Precinct (GTP), Pigdons Road, Waurn Ponds, Geelong, Victoria 3217, Australia

2Professor, Department of Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh, India-160012

*Corresponding Author:
Dr. Jagat R. Kanwar, MSc, PhD
Associate Professor of Immunology & Cell Biology
Head, Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (LIMBR)
Centre for Biotechnology and Interdisciplinary Biosciences (BioDeakin)
Institute for Technology & Research Innovation (ITRI)
Geelong Technology Precinct (GTP), Deakin University
Pigdons Road, Waurn Ponds, Geelong, Victoria 3217, Australia
Tel: 0061-3 -5227 1148
Fax: 0061-3-5227 3402
E-mail: [email protected]

Received date: January 03, 2012; Accepted date: March 05, 2012; Published date: March 07, 2012

Citation: Kanwar JR, Samarasinghe RM, Sehgal R, Kanwar RK (2012) Nano- Lactoferrin in Diagnostic, Imaging and Targeted Delivery for Cancer and Infectious Diseases. J Cancer Sci Ther 4: 031-042. doi:10.4172/1948-5956.1000107

Copyright: © 2012 Kanwar JR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Lactoferrin (Lf) is a natural occurring iron binding protein present in many mammalian excretions and involved in various physiological processes. Lf is used in the transport of iron along with other molecules and ions from the digestive system. However its the modulatory functions exhibited by Lf in connection to immune response, disease regression and diagnosis that has made this protein an attractive therapeutic against chronic diseases. Further, the exciting potentials of employing nanotechnology in advancing drug delivery systems, active disease targeting and prognosis have also shown some encouraging outcomes. This review focuses on the role of Lf in diagnosing infection, cancer, neurological and inflammatory diseases and the recent nanotechnology based strategies.

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