alexa Nasopharyngeal Carcinoma Associated with Lassa Fever Virus Infection | OMICS International | Abstract
ISSN: 2157-7420

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Review Article

Nasopharyngeal Carcinoma Associated with Lassa Fever Virus Infection

Obasikene G1*, Kpolugbo J2, Ibiam FA3, Adobamen PROC4, Esezebor E2, Tobin Ek5, Asogun DA5, Obasikene CN6, Saiki BO1, Ayeke JO1 and Agbonifo M1

1ENT Unit, Irrua Specialist Teaching Hopsital, Irrua, Nigeria

2Department of Surgery, Irrua Specialist Teaching Hopsital, Irrua, Nigeria

3Ear, Nose and Throat unit, Federal Medical Center Owerri, Imo State South East Nigeria, Nigeria

4Department of Oto-Rhino-Laryngology, University of Benin Teaching Hospital, Benin City, Nigeria

5Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Nigeria

6Department of Radiology, University of Benin Teaching Hospital, Benin City, Nigeria

*Corresponding Author:
Obasikene G
ENT Unit, Irrua Specialist Teaching Hopsital, Irrua
Tel: +234(8)37029753
E-mail: [email protected]

Received Date: December 09, 2013; Accepted Date: February 18, 2014; Published Date: February 25, 2014

Citation: Obasikene G, Kpolugbo J, Ibiam FA, Adobamen PROC, Esezebor E, et al. (2014) Nasopharyngeal Carcinoma Associated with Lassa Fever Virus Infection. J Health Med Informat 5:147. doi: 10.4172/2157-7420.1000147

Copyright: © 2014 Obasikene G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Nasopharyngeal carcinoma (NPC) is a head and neck cancer usually found in the nasopharynx and arising mostly from Fossa Rosenmueller. The aetiopathogenesis has been linked to environmental factors, genetic susceptibility and Epstein–Barr virus infection. However, more recent data state that all the three subtypes of NPC tumors are associated to Epstein–Barr virus infection (EBV). Therefore we present cases of NPCs associated to Lassa fever virus infection. Lassa fever virus is a member of the arena viridae group. It is endemic in Edo state, which accounts for the highest number of cases of the disease in the country. Despite the magnitude of the mortality rate of this disease in Edo land, not much has been done by any institute to assess the long time effect of the disease on the endemic communities. We hence present two known cases of NPC in two confirmed cases of Lassa fever virus patients some years prior to the diagnoses of the NPC.

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