alexa Natural Bioactive Sterol 5α,8α-endoperoxides
ISSN: 2161-0444

Medicinal Chemistry
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Natural Bioactive Sterol 5α,8α-endoperoxides as Drug Lead Compounds

Ming Bu1, Burton B Yang2 and Liming Hu1*

1College of Life Science and Bioengineering, Beijing University of Technology, No.100, Pingleyuan, Chaoyang, Beijing, 100124, China

2Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

*Corresponding Author:
Liming Hu
College of Life Science and Bioengineering
Beijing University of Technology
No.100, Pingleyuan, Chaoyang
Beijing, 100124,China
Tel: 86-10-67396211
Fax: 86-10-67396211
E-mail: [email protected]

Received date: June 27, 2014; Accepted date: September 10, 2014; Published date: September 15, 2014

Citation: Ming Bu, Yang BB, Hu L (2014) Natural Bioactive Sterol 5a,8a- endoperoxides as Drug Lead Compounds. Med chem 4:709-716. doi:10.4172/2161-0444.1000217

Copyright: 2014 Ming Bu, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The natural product sterol 5α,8α-endoperoxides are structural different from general sterols. These compounds belong to the group of oxidized sterol derivatives and contain a 5α,8α-endoperoxide bond in addition to the fragments characteristic of original sterols. Many researches have reported that sterol 5α,8α-endoperoxides have potential bioactivities, including antioxidant, antimicrobial, anti-tumor activity, immunomodulatory activity, inhibitory hemolytic activity and anti-inflammatory activity etc. The review discussed the structures, properties, bioactivity and synthetic methods of sterol 5α,8α-endoperoxides. The natural peroxides are valuable sources in the development of novel bioactive agents.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version