alexa Natural Regulatory T Cells in Some Parasitic Diseases
ISSN: 2155-9597

Journal of Bacteriology & Parasitology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Natural Regulatory T Cells in Some Parasitic Diseases

Raida S Yahya1, Fahmida Khatoon2*,Soha I Awad2, Nashwa K Abousamra3, Hanan Azzam3, Gehan Atia4, Hatim A El-Baz5, Rokaiah Anwar6 and Mona Arafa7

1Laboratory Department, Children Hospital, Faculty of Medicine, Mansoura, Egypt

2Department of Parasitology, Faculty of Medicine, Mansoura, Egypt and Department Medical Parasitology, Faculty of Medicine, Northern Border University, Arar, KSA

3Department of Clinical Pathology, Faculty of Medicine, Mansoura, Egypt

4Department of Pediatrics, Children Hospital, Faculty of Medicine, Mansoura, Egypt

5Biochemistry Department, Genetic Engineering and Biotechnology Division, National Research Centre, Cairo, Egypt & Clinical Biochemistry Department, Faculty of Medicine, North Jeddah Branch, King Abdulaziz University, KSA

6Department of Internal Medicine, Faculty of Medicine, Mansoura, Egypt

7Department of Tropical Medicine, Faculty of Medicine, Mansoura, Egypt

*Corresponding Author:
Fahmida Khatoon
Department Medical Parasitology
Faculty of Medicine, Northern Border University, Arar, KSA
Tel: 0506248128
E-mail: [email protected]

Received date: March 05, 2014; Accepted date: November 26, 2014; Published date: November 28, 2014

Citation: Khatoon F, Yahya RS, Awad SI, Abousamra NK, Azzam H, et al. (2015) Natural Regulatory T Cells in Some Parasitic Diseases. J Bacteriol Parasitol 6:210. doi: 10.4172/2155-9597.1000210

Copyright: © 2015 Fahmida K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

 Parasitic infection in human alimentary tract causes a significant change in immune system through its continuous antigens secretion. The aim of this study was to estimate the change in natural regulatory T cell population in peripheral blood of patients infected with different types of alimentary tract parasites. Regulatory T cells (CD4+CD25+Foxp3+) were detected in eighty patients infected with intestinal parasites and forty healthy volunteers using flow cytometry technique. Statistical analysis showed a significant increase in regulatory T cell percentage in infected patients compared to healthy group (P<0.001). Patients infested with Giardia showed significantly higher CD4+CD25+Foxp3+ cell percentages than those infested with other parasites (P<0.001). Also, mixed infestation showed significantly higher CD4+CD25+Foxp3+ cell percentages than single infestation. In conclusion, natural regulatory T cell frequencies (CD4+CD25+Foxp3+) increase significantly in patients with parasitic diseases compared to healthy controls. The higher levels were associated with mixed infection compared to single infection, and in older than younger patients.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords