alexa Neuroprotective Treatment Strategies for Delayed Cerebral Ischemia after Subarachnoid Hemorrhage - Review of Literature and Future Prospects
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

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Review Article

Neuroprotective Treatment Strategies for Delayed Cerebral Ischemia after Subarachnoid Hemorrhage - Review of Literature and Future Prospects

Thomas Westermaier*

Department of Neurosurgery, University Hospital Wuerzburg, Josef-Schneider-Str. 11, 97080 Wuerzburg, Germany

Corresponding Author:
Thomas Westermaier
University Hospital Wuerzburg
Department of Neurosurgery
Josef-Schneider-Str. 1197080 Wuerzburg, Germany
Tel: +49-931-24527
Fax: +49-931-24551
E-mail: [email protected]

Received date: November 28, 2013; Accepted date: December 23, 2013; Published date: December 31, 2013

Citation: Westermaier T (2013) Neuroprotective Treatment Strategies for Delayed Cerebral Ischemia after Subarachnoid Hemorrhage – Review of Literature and Future Prospects. J Neurol Neurophysiol 5:183. doi:10.4172/2155-9562.1000183

Copyright: © 2013 Westermaier T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



This article reviews experimental and clinical data on the use of various neuroprotective agents and therapeutic measures after aneurysmal subarachnoid hemorrhage (SAH). While calcium antagonists have been used in the past and are still part of the standard treatment regimen in most departments involved in the treatment of SAH, other classes of drugs and various other methods have been tested for their potential to inhibit delayed ischemia after SAH. This article reviews the literature about clinical studies about the efficacy of various neuroprotective agents and methods including statins, steroids and Endothelin-antagonists and other - alternative - methods like cisternal lavage, intrathecal drug delivery and hypercapnia, offering future perspectives for the treatment of this hazardous disease


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