alexa Neurotoxic Manifestation of Snake Bite in Bangladesh | OMICS International | Abstract
ISSN: 2161-0495

Journal of Clinical Toxicology
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Research Article

Neurotoxic Manifestation of Snake Bite in Bangladesh

Mohammad Robed Amin1*, SM Hasan Mamun2, Nazmul Hasan Chowdhury3, M Rahman4, Mohammad Ali5, Abdullah Al Hasan1, MR Rahman6 and M A Faiz7

1Dhaka Medical College, Bangladesh

2Chittagong Medical College, Bangladesh

3Comilla Medical College, Bangladesh

4Shahabuddin Medical College, Dhaka, Bangladesh

5Bogura Medical College, Bangladesh

6Begum Khaleda Zia Medical College, Dhaka, Bangladesh

7Sir Salimullah Medical Medical College, Dhaka, Bangladesh

*Corresponding Author:
Dr. Md. Robed Amin
Assistant Professor of Medicine, Department of Medicine
Dhaka Medical College, Dhaka, Bangladesh
Tel: 8801711725787
E-mail: [email protected]

Received date: December 20, 2013; Accepted date: March 26, 2014; Published date: March 31, 2014

Citation: Robed Amin A, Hasan Mamun SM, Chowdhury NH, Rahman M, Ali M, et al. (2014) Neurotoxic Manifestation of Snake Bite in Bangladesh. J Clin Toxicol 4:185 doi: 10.4172/2161-0495.1000185

Copyright: © 2013 Jung YG. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Introduction: Snake bite is a potentially life threatening emergency situation physician has to encounter in rural areas of tropical countries in South-East Asia including Bangladesh. Among the venomous snakes in Bangladesh, Neurotoxic snakes like Cobra and Krait are the commonest. In this study neurotoxic manifestation of venomous snakes are clinically observed.

Methods: In this series a total 35 snakebite patients with neurological features from May 1999 to June 2001 were included and preexisting neurological cases were excluded.

Results: Among the 537 total snake bite cases, the neurotoxic snake bite was 10% with 51 cobra bite and 12 kraits bite. The victims age are in the range of 3.5 years to 85 years with 70% cases are under 30 years of old. There is slight male preponderence with almost same number of bite at home and outside. The common clinical neurotoxic features are ptosis, (100%) external ophthalmoplegia, dysphagia, dysphonia and broken neck sign. The chest movements were reduced in 20 % cases. All 35 cases (100%) were treated with Haffkine polyvalent anti snake venom with 8.6% cases needed 2nd dose. All 35 cases with neurotoxic features were also treated with anti cholinesterses (100%) and among them 14.2% needed ventilatory support. Anti-snake venom reaction was very common in the with pyrogenic reaction (80.64%) and anaphylactic reaction (64.51%). The outcome of snake bite was excellent with 97% recovery with one residual neurological deficit and no fatality.

Conclusion: The neurotoxic snake bite has definite characteristics neurological sign and symptoms which could lead to fatality with respiratory paralysis.


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