alexa New Genetic Approach in Early Detection of Cancer
ISSN-2155-9929

Journal of Molecular Biomarkers & Diagnosis
Open Access

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Review Article

New Genetic Approach in Early Detection of Cancer

Rafal Al-Rawi*

Department of Pathology, College of Pharmacy, Hawler Medical University, Iraq

Corresponding Author:
Rafal Al-Rawi
Departments of Pathology, College of Pharmacy
Hawler Medical University, Iraq
Tel: 009647504441735; 009647503648209
E-mail: [email protected]; [email protected]

Received date: July 05, 2016; Accepted date: July 26, 2016; Published date: July 28, 2016

Citation: Al-Rawi R (2016) New Genetic Approach in Early Detection of Cancer. J Mol Biomark Diagn 7:292. doi:10.4172/2155-9929.1000292

Copyright: © 2016 Al-Rawi R. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Cancer is a major health problem all over the world, the main obstacle facing cancer prevention is a lack of precise approach for early detection and prevention strategies of the disease. All previous works on cancer dealt with only infected patients. New technique under accurate statistical experimental design must be developed in order to early diagnose of the disease. This will be done through molecular characterization of genomic DNA of thousands of cancer infected as well as healthy people living in high and low risk environmental conditions. Genetic variations (differences) for resistant/tolerant versus susceptible individuals to cancer incidence exist within communities and various regions. The result of such molecular genetic variations will play role in answering the questions of why do the majority of people living in high environmental risk area never get cancer? And why do some people living in low environmental risk area get cancer? Previous studies reported that the current theory dealing with cancer cause is that long periods of exposure to environmental risk factors (carcinogenic, pollutants, smoke, chemical and others) have had a major effect in modifying the constitution of the genome (gene) through mitosis mutation. Contrary to that, the current article hypothesizes that cancer occur as a result of presence of sensitive gene(s) that inherited by infected individuals coupled and interacted with environmental causes. So it is a vital issue to investigate the relation between resistant versus susceptible individuals to cancer incidence and their molecular characterizations (genetic make-up) to identify the molecular genetic differences (genes or alleles, that are associated with resistance or susceptibility to cancer), as molecular genetic markers to be used as early detection of individuals susceptible to cancer.

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