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New Therapeutic Advances in Chronic Lymphocytic Leukemia | OMICS International | Abstract
ISSN: 2329-6917

Journal of Leukemia
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New Therapeutic Advances in Chronic Lymphocytic Leukemia

Ghayathri Jeyakumar1* and Alessandra Ferrajoli2

1Fellow, Leukemia Department, MD Anderson Cancer Center

2Assistant Professor, Leukemia Department, MD Anderson Cancer Center

*Corresponding Author:
Dr. Alessandra Ferrajoli
Associate Professor
Leukemia Department
The University of Texas MD Anderson Cancer Center1515 Holcombe Blvd. Houston
TX 77030-4009, USA
Tel:(713) 792-2063
Email:[email protected]

Received date: May 14, 2014; Accepted date: July 22, 2014;; Published date: July 25, 2014

Citation: Jeyakumar G, Ferrajoli A (2014) New Therapeutic Advances in Chronic Lymphocytic Leukemia. J Leuk (Los Angel) 2:144. doi: 10.4172/2329-6917.1000144

Copyright: ©2014 Jeyakumar G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Treatment of Chronic Lymphocytic Leukemia (CLL) is entering a new era. In the last 5 years, several new exciting drugs have entered the realm in hopes for a success in curing the disease. The drugs fall into different classes such as BTK inhibitors, BCL-2 inhibitors, CD 20 Antibody, PI3 Kinase inhibitors, and Syk inhibitors. Numerous studies have shown that these agents have clinical activity both as initial therapy and as treatment of recurrent disease. Novel strategies combining or sequencing new agents with established chemotherapy and chemoimmunotherapies combinations are likely to change the treatment of CLL in the near future.


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