alexa Niacin, the Internet, and Urine Drug Testing: A Cause of Acute Liver Failure | OMICS International | Abstract
ISSN: 2161-0495

Journal of Clinical Toxicology
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Case Report

Niacin, the Internet, and Urine Drug Testing: A Cause of Acute Liver Failure

Sheila Eswaran, Nicole Alvey, Sameh Fayek, Nikunj Shah and Edie Chan*

Rush University Medical Center, USA

*Corresponding Author:
Edie Chan
Assistant Professor
Rush University Medical Center, USA
E-mail: [email protected]

Received date: August 03, 2013; Accepted date: September 16, 2013; Published date: September 23, 2013

Citation: Eswaran S, Alvey N, Fayek S, Shah N, Chan E (2013) Niacin, the Internet, and Urine Drug Testing: A Cause of Acute Liver Failure. J Clin Toxicol 3:167. doi: 10.4172/2161-0495.1000167

Copyright: © 2013 Eswaran S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Niacin (Vitamin B3) is a naturally occurring human nutrient found in abundance in meat, yeast, vegetables, and seeds. Deficiencies of this vitamin lead to pellagra and it has also been found to be useful in the treatment of hypercholesterolemia. As the use of niacin has increased, several cases of hepatotoxicity have been reported resulting in the recommendation to initiate treatment with a lower dose and to monitor liver function test. We report two cases of hepatotoxicty in young adults who attempted to pass a drug screening test based on faulty internet advice to use niacin.

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