No Evidence of HSV Presence in the Serum of Vitiligo Patients*Corresponding Author: Xing-Hua Gao, Department of Dermatology, No. 1 Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China, Tel: +86-24-83282525, Fax: +86-24-83282525, Email: [email protected]
Received Date: Apr 09, 2014 / Accepted Date: May 23, 2014 / Published Date: May 25, 2014
Citation: Liu Z, Qi RQ, Zhao LS, Sun XD, Dong DY, et al. (2014) No Evidence of HSV Presence in the Serum of Vitiligo Patients. Pigmentary Disorders 1:105.DOI: 10.4172/2376-0427.1000105
Copyright: © 2014 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Vitiligo is mostly regarded as a consequence of autoimmune response, while the triggering factors remain to be determined. We checked the presence of HSV specific DNA, and IgG and IgM antibodies against HSV, in serum of 90 vitiligo patients by PCR and chemiluminescence methods, respectively. No HSV specific DNA was detected in vitiligo of any types or stages. The seropositivity of antibodies against HSV was similar between the patients and controls. Other approaches should be tried to clarify the role of HSV in the pathogenesis of vitiligo.