alexa No Evidence of HSV Presence in the Serum of Vitiligo Patients | OMICS International | Abstract
ISSN: 2376-0427

Dermatology and Dermatologic Diseases
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Previously: Journal of Pigmentary Disorders

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Research Article

No Evidence of HSV Presence in the Serum of Vitiligo Patients

Zhe Liu1,2, Rui-Qun Qi1, Lian-Shuang Zhao3, Xiao-Dong Sun1, Da-Yong Dong4, Gui-Hua Li1, Ya-Ni Lv1, Long Geng1, Hong-Duo Chen1 and Xing-Hua Gao1*
1Department of Dermatology, No. 1 Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China
2Department of Dermatology, Central Hospital of Shenyang Sujiatun District, 31 Begonia Street, Sujiatun District, Shenyang 110101, China
3Department of Clinical Laboratory, No. 1 Hospital of China Medical University, 155 North Nanjing Street, Shen yang 110001, China
4State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Feng Tai Dongdajie Street, Beijing 100071, PR China
Corresponding Author : Xing-Hua Gao
Department of Dermatology
No. 1 Hospital of China Medical University
155 North Nanjing Street, Shenyang 110001, China
Tel: +86-24-83282525
Fax: +86-24-83282525
E-mail: [email protected]
Received April 09, 2014; Accepted May 23, 2014; Published May 25, 2014
Citation: Liu Z, Qi RQ, Zhao LS, Sun XD, Dong DY, et al. (2014) No Evidence of HSV Presence in the Serum of Vitiligo Patients. Pigmentary Disorders 1:105. doi:10.4172/2376-0427.1000105
Copyright: © 2014 Liu Z, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Vitiligo is mostly regarded as a consequence of autoimmune response, while the triggering factors remain to be determined. We checked the presence of HSV specific DNA, and IgG and IgM antibodies against HSV, in serum of 90 vitiligo patients by PCR and chemiluminescence methods, respectively. No HSV specific DNA was detected in vitiligo of any types or stages. The seropositivity of antibodies against HSV was similar between the patients and controls. Other approaches should be tried to clarify the role of HSV in the pathogenesis of vitiligo.

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