Nodular Melanoma-Like Superficial Spreading Melanoma Arising from Intradermal Unna Nevus-Can Incomplete Oncogenic-senescence be Responsible for Non-hierarchical Melanomagenesis?
|Betul Tas1*, Ozgur Pilanci2, Yazgi Koy3 and Umit Seza Tetikkurt3|
|1Department of Dermatology Bagcilar Research and Training Hospital, Turkey|
|2Department of Plastic Aesthetic and Reconstructive Surgery, Bagcilar Research and Training Hospital,Turkey|
|3Department of Pathology, Bagcilar Research and Training Hospital , Turkey|
|Corresponding Author :||Betul Tas
Department of Dermatology, Bagcilar Research and Training Hospital
Atakoy 7-8. Kisim, Marti Sitesi, 14/105, Bakirkoy/Istanbul, Turkey- 34156
Tel: (+¬¬90) 212-4404000
Fax: (+90) 212-4404000
E-mail: [email protected]
|Received April 06, 2015; Accepted April 17, 2015; Published April 25, 2015|
|Citation: Tas B, Pilanci O, Koy Y, Tetikkurt US (2015) Nodular Melanoma-Like Superficial Spreading Melanoma Arising from Intradermal Unna Nevus-Can Incomplete Oncogenic-senescence be Responsible for Non-hierarchical Melanomagenesis? Pigmentary Disorders 2:179. doi:10.4172/2376-0427.1000179|
|Copyright: © 2015 Tas B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
We report a 70-year-old woman who presented a superficial spreading malignant melanoma with a nodular melanoma appearance, located on her leg. Most common clinicopathological types of malignant melanoma are lentigo maligna, superficial spreading, nodular, and acral lentiginous melanoma. Unusual variants of melanoma are rare but important. These are amelanotic melanoma, neurotropic melanoma, desmoplastic melanoma, metastatic melanoma, invisible melanoma, balloon cell melanoma, melanoma arising within a benign nevus and pedunculated melanoma. The lesion of our patient simulated a nodular or a pedunculated melanoma clinically, but its histopathological examination showed a superficial spreading melanoma arising from the surface of an Unna nevus. To the best of our knowledge, such misleading nodular appearance of a superficial melanoma arising from an intradermal nevus of Unna which seems to be a unique finding has not been reported previously.