alexa Nomogram for Overall Survival of Japanese Patients with Bone Metastatic Prostate Cancer | OMICS International | Abstract
ISSN: 2168-9857

Medical & Surgical Urology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Nomogram for Overall Survival of Japanese Patients with Bone Metastatic Prostate Cancer

Yasuhide Miyoshi1*, Kazumi Noguchi1, Masahiro Yanagisawa2, Masataka Taguri3, Satoshi Morita3, Ichiro Ikeda4, Kiyoshi Fujinami1, Takeshi Miura5, Kazuki Kobayashi6, Yoshinobu Kubota2 and Hiroji Uemura2

1Department of Urology, Yokohama City University Medical Center, Yokohama, Japan

2Department of Urology, Yokohama City University School of Medicine, Yokohama, Japan

3Department of Biostatistics and Epidemiology, Yokohama City University School of Medicine, Yokohama, Japan

4Department of Urology, Yokohama Minami Kyousai Hospital, Yokohama, Japan

5Department of Urology, Kanagawa Cancer Center, Yokohama, Japan

6Department of Urology, Yokosuka Kyosai Hospital, Yokosuka, Japan

*Corresponding Author:
Yasuhide Miyoshi
Department of Urology, Yokohama City University Medical Center
4-57 Urafune-cho Minami-ku, Yokohama 232-0024, Japan
Tel: +81-45-261-5656
E-mail: [email protected]

Received date : December 16, 2013; Accepted date : May 29, 2014; Published date : June 02, 2014

Citation: Miyoshi Y, Noguchi K, Yanagisawa M, Taguri M, Morita S, et al. (2014) Nomogram for Overall Survival of Japanese Patients with Bone Metastatic Prostate Cancer. Med Surg Urol 3:135. doi:10.4172/2168-9857.1000135

Copyright: © 2014 Miyoshi Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Objective: We analyzed the relationship between prostate cancer outcome and pretreatment clinical factors, and developed a prognostic nomogram for Overall Survival (OS) of patients with bone metastasis.

Methods: Beginning in 1993 to 2011, 463 consecutive prostate cancer patients with bone metastasis were treated. Data sets from 361 patients were used to develop the nomogram (training data), and data sets of 102 patients were used for validation of the nomogram (validation data). Using the external validation data set, the nomogram was assessed for discriminatory ability, and the predictions were assessed for calibration accuracy by plotting actual survival against predicted risk.

Results: Of 361 training data set, 205 (56.8%) patients died, 169 (46.8%) deaths of which were due to prostate cancer. The Median follow-up of patients were 55.2 months. In multivariate analysis, patient age, serum PSA, clinical T stage, extent of disease on bone scan (EOD), and biopsy Gleason sum were independent prognostic factors. We developed a prognostic model for prostate cancer patients with bone metastasis, consisting of these five factors. This nomogram can be used to estimate 1-, 3-, and 5-year survival probability. External validation of this model using 102 validation data sets showed reasonable accuracy (c-index 0.719), although with slight underestimation.

Conclusion: Our pretreatment prognostic nomogram might be useful for Japanese prostate cancer patients with bone metastasis

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals


Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T


[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7