alexa Non Adherence and Contributing Factors among Ambulatory
ISSN: 2167-1052

Advances in Pharmacoepidemiology and Drug Safety
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Non Adherence and Contributing Factors among Ambulatory Patients with Anti Diabetic Medications in Adama Referral Hospital

Gelaw BK*, Mohammed A, Tegegne GT, Defersha AD, Fromsa M , Tadesse E, Thrumurgan G and Ahmed M
Department of Pharmacy, College of Medicine and Health Science, Ambo University, Oromia, Ethiopia
*Corresponding Author : Gelaw BK
Department of Pharmacy, College of Medicine and Health Science
Ambo University, Oromia, Ethiopia
Tel: 251-911516669
E-mail: [email protected]
Received August 14, 2014; Accepted October 25, 2014; Published October 27,2014
Citation: Gelaw BK, Mohammed A, Tegegne GT, Defersha AD, Fromsa M, et al.(2014) Non Adherence and Contributing Factors among Ambulatory Patients with Anti Diabetic Medications in Adama Referral Hospital. Adv Pharmacoepidemiol Drug Saf 3:169. doi:10.4172/2167-1052.1000169
Copyright: © 2014 Gelaw BK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: The term diabetes mellitus describes metabolic disorders of multiple etiologies characterized by hyperglycemia with disturbances of carbohydrates, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. Anti-diabetic medications are integral for glycemic control in diabetes. Non adherence to drugs can alter blood glucose levels, resulting in complications. The objective of this study was to determine the magnitude of non-adherence and its contributing factors among diabetic patients attending the diabetic clinic in Adama hospital.

Methods: This descriptive cross-sectional study was carried out among patients with diabetes mellitus attending the diabetes mellitus clinic of Adama referral hospital. Every other patient was selected and data regarding their medication adherence was collected using a structured interview. Data analysis was carried out using SPSS-16.

Result: The response rate from this study was 98.3%. A total of 270 patients were interviewed; 51.5% were males. A total of 68.1% of the patients included in the study were married. 14% were younger than 40 years of age,50% were between 40 and 60 years of age. 21.8% of the participants ascribed their non-adherence to forgetting to take their medications. Patients with duration of diabetes ≤ 5 years (82.07%) were more compliant to their medication than those with >5 years 60.8%, which was found to be statistically significant (P=0.003). Insulin 47% and glibenclamide plus metformine 43.7% were the most commonly prescribed mono and combination therapies respectively. Common co morbid conditions include, Hypertension 148(54.82%), Visual impairment 89(32.96%). The proportion of male patients adherent to their anti-diabetic medications was found to be lower 69.78% compared to the female patients (74.81%), but the difference was not statistically significant (p>0.05).

Conclusion: Most diabetic patients are currently being managed with the most effective available drugs. However as the result from this study indicates the desired blood sugar level could not be controlled and maintained adequately. This was because of poor adherence with the prescribed drug regimen and poor knowledge and practice of successful self management.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version