alexa Non-coding Vibration in Circadian Oscillation | OMICS International | Abstract
ISSN: 2379-1764

Advanced Techniques in Biology & Medicine
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Non-coding Vibration in Circadian Oscillation

Utpal Bhadra1*, Pradipta Patra1 and Manika Pal-Bhadra2

1Functional Genomics and Gene Silencing Group, Centre for Cellular and Molecular Biology, Hyderabad-500007, India

2Centre for Chemical Biology, Indian Institute of Chemical Technology, Hyderabad-500007, India

*Corresponding Author:
Utpal Bhadra
Functional Genomics and Gene Silencing Group
Centre for Cellular and Molecular Biology
Uppal Road, Hyderabad, India-50007
Tel: 91-40-27192513
Fax: 91-40-27160591
E-mail: [email protected]

Received date: July 11, 2017; Accepted date: August 03, 2017; Published date: August 09, 2017

Citation: Bhadra U, Patra P, Pal-Bhadra M (2017) Non-coding Vibration in Circadian Oscillation. Adv Tech Biol Med 5:236. doi:10.4172/2379-1764.1000236

Copyright: © 2017 Bhadra U, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Abstract

Neuron driven physiological activities such as sleep, feeding, energy consumption are controlled by light sensitive central clock genes in the pacemaker neurons in the brain. Multiple epigenetic events including post-transcriptional regulation, splicing, polyadenylation, mature mRNA editing and stability of translation products are the main vibrators for circadian oscillation with the instructive role of various sets of non-coding small regulatory RNA. Here, we sum up the basic role of small regulatory RNA and their epigenetic circuits in brain clock activity.

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