alexa Non-Functioning Paraganglioma Located at the Renal Hilu
ISSN: 2329-6577

Biological Systems: Open Access
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Case Report

Non-Functioning Paraganglioma Located at the Renal Hilus: Case Report

Mattia Garancini1*, Giovanni Cesana2, Camillo Di Bella3, Antonio Tancredi2, Adelio Valtorta2, Maria Enrica Giovenzana4 and Massimo Beltramo2
1Department of General Surgery, San Gerardo Hospital, University of Milano-Bicocca, Monza Milano, Italy
2Department of Surgery and Urology, Vittorio Emanuele III Hospital, Carate Brianza, Milano, Italy
3Department of Pathology, Vittorio Emanuele III Hospital, Carate Brianza ,Milano, Italy
4Department of Nephrology, San Gerardo Hospital, University of Milano-Bicocca, Monza Milano, Italy
*Corresponding Author : Mattia Garancini
Department of Surgery
Ospedale san Gerardo via Pergolesi 33
Monza, 20052, Milano, Italy
Tel: 0039 039 2333600
Fax: 0039 039 2333600
E-mail: [email protected]
Received April 02, 2012; Accepted April 08, 2012; Published April 11, 2012
Citation:Garancini M, Cesana G, Bella CD, Tancredi A, Valtorta A, et al. (2012) Non-Functioning Paraganglioma Located at the Renal Hilus: Case Report. Biol Syst Open Access 1:101. doi:10.4172/2329-6577.1000101
Copyright: © 2012 Garancini M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Paragangliomas are a type of neuroendocrine tumor derived from embryonic neural crest. They are mostly found in the adrenal glands (pheocromocytomas) and in the extra-adrenal paraganglia of the autonomic nervous system (extra-adrenal paraganglioma). Paragangliomas arising from the kidney or in the renal hilus are very rare and a preoperative diagnosis is hardly made. We present the case of a 44-years-old female with a 1-week history of feeling a mass in the right-upper side of the abdomen and no other symptoms. Computerized tomography (CT) demonstrated a round solid extra-adrenal mass located at the renal hilus. Laparotomy was performed with the intention of removing the mass and providing a histopathological diagnosis. Microscopic examination revealed a characteristic “Zellballen” organization and the presence of Sustentacular Cells S-100 positive. On these findings, extra-adrenal paraganglioma of the renal hilus was diagnosed histologically. The patient did not receive any further treatment other than surgery. The intervention was safe and effective. On a 20 months follow-up she results healthy and disease-free.

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