alexa Non-Hypersplenism Causes of Peripheral Cytopenias in Patients with Cirrhotic Portal Hypertension: A Review
ISSN: 2167-1095

Journal of Hypertension: Open Access
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Review Article

Non-Hypersplenism Causes of Peripheral Cytopenias in Patients with Cirrhotic Portal Hypertension: A Review

Yunfu Lv1,3, Wan Yee Lau1,2*, Jie Deng1,3, YeJuan Li1,3 and Yonghong Dong4

1Department of General Surgery, Hainan Province People’s Hospital, Haikou (570311), China

2Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China

3Hainan University, Haikou, 570228, China

4Department of General Surgery, Shanxi Province People's Hospital, Taiyuan, (030001), China

*Corresponding Author:
Wan Yee Lau
Department of General Surgery
Hainan Province People’s Hospital
Haikou (570311), China
E-mail: [email protected]

Received date Mar 5, 2016; Accepted date May 11, 2016; Published date May 16, 2016

Citation: Lv Y, Lau WY, Deng J, Li JY, Dong Y (2016) Non-Hypersplenism Causes of Peripheral Cytopenias in Patients with Cirrhotic Portal Hypertension: A Review. J Hypertens 5:223. doi:10.4172/2167-1095.1000223

Copyright: © 2016 Lv Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Hypersplenism and non-hypersplenism factors, either alone or in combination, can cause peripheral cytopenias in patients with cirrhotic portal hypertension. Although non-hypersplenism factors account for only a small proportion of patients, they do exist. When peripheral cytopenias do not improve, or fail to improve adquately, or even become worse after splenectomy in these patients, non-hypersplenism factors should be considered. This review aims to provide an overview of non-hypersplenism factors.


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