alexa Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s Disease| Abstract

ISSN: 2155-983X

Journal of Nanomedicine & Biotherapeutic Discovery

  • Research Article   
  • J Nanomedine Biotherapeutic Discov 2014, Vol 4(2): 128
  • DOI: 10.4172/2155-983X.1000128

Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s Disease

Paul Zarogoulidis1,2, Ioannis Kioumis1, Theodora Tsiouda4, Nikolaos Pezirkianidis1,7, Christos Ritzoulis5, Haidong Huang6, Wolfgang Hohenforst-Schmidt7, Dionysios Spyratos1, Konstantinos Porpodis1, Georgia Pitsiou1, Sofia Lampaki1, John Organtzis1, Bianca Kathryn Malecki1,8,9, Sindre Ervik Saetre1,8,9, Konstantinos Zarogoulidis1 and Marek Malecki9,10*
1Aristotle University of Thessaloniki, Thessaloniki, EU, Greece
2University of Duisburg-Essen, Duisburg, EU, Germany
3Theagenio Anticancer Hospital, Thessaloniki, EU, , Greece
4Alexander Technological Educational Institute, Thessaloniki, EU, , Greece
5II Military University Hospital, Shanghai,, , China
6Coburg Regional Hospital, EU, , Germany
7Private Practice, Serres, EU, , Greece
8Jagiellonian University Medical College, Krakow, EU, Poland
9Phoenix Biomolecular Engineering Foundation, San Francisco, CA,, , USA
10University of Wisconsin, , Madison, WI, USA
*Corresponding Author : Marek Malecki M.D., Ph.D., Phoenix Biomolecular Engineering Foundation, San Francisco, CA 91105, USA, Tel: 4157134370, Fax: 4157134371, Email: [email protected]

Received Date: Jul 04, 2014 / Accepted Date: Jul 23, 2014 / Published Date: Jul 25, 2014

Abstract

Background: Inflammatory diseases such as; crohn`s disease and ulcerative colitis are responsible for the malnutrition of the patients. These patients due to structural damage within the gastrointestinal tract do not absorb nutrients. Cystic fibrosis is a hereditary disease where the viscosity of mucus induces organ deficiency and nutrition malnutrition.
Materials and Methods: A novel polymer tube was constructed in order to evaluate the rheology of different types of nutrients. Results: The current 3D model simulates both light and severe disease with the different types of “traps” that have been constructed within it.
Conclusion: Modification of the different nutrients will elicit the proper future modifications that the industry should make for the patients with these underlying diseases.

Keywords: Cystic Fibrosis; Crohn`s Disease; Ulcerative Colitis; Nutrition model; Bioengineering; Biotechnology

Citation: Zarogoulidis P, Kioumis I, Tsiouda T, Pezirkianidis N, Ritzoulis C (2014) Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s Disease. J Nanomedine Biotherapeutic Discov 4: 128. Doi: 10.4172/2155-983X.1000128

Copyright: © 2014 Zarogoulidis P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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