Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s DiseasePaul Zarogoulidis1,2, Ioannis Kioumis1, Theodora Tsiouda4, Nikolaos Pezirkianidis1,7, Christos Ritzoulis5, Haidong Huang6, Wolfgang Hohenforst-Schmidt7, Dionysios Spyratos1, Konstantinos Porpodis1, Georgia Pitsiou1, Sofia Lampaki1, John Organtzis1, Bianca Kathryn Malecki1,8,9, Sindre Ervik Saetre1,8,9, Konstantinos Zarogoulidis1, and Marek Malecki9,10*
- *Corresponding Author:
- Marek Malecki
M.D., Ph.D., Phoenix Biomolecular Engineering Foundation
San Francisco, CA 91105, USA
Email: mm-pbmef; [email protected]
Received Date: July 04, 2014; Accepted Date: July 23, 2014; Published Date: July 25, 2014
Citation: Zarogoulidis P, Kioumis I, Tsiouda T, Pezirkianidis N, Ritzoulis C (2014) Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s Disease. J Nanomedine Biotherapeutic Discov 4:128. doi: 10.4172/2155-983X.1000128
Copyright: © 2014 Zarogoulidis P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Inflammatory diseases such as; crohn`s disease and ulcerative colitis are responsible for the malnutrition of the patients. These patients due to structural damage within the gastrointestinal tract do not absorb nutrients. Cystic fibrosis is a hereditary disease where the viscosity of mucus induces organ deficiency and nutrition malnutrition.
Materials and Methods: A novel polymer tube was constructed in order to evaluate the rheology of different types of nutrients. Results: The current 3D model simulates both light and severe disease with the different types of “traps” that have been constructed within it.
Conclusion: Modification of the different nutrients will elicit the proper future modifications that the industry should make for the patients with these underlying diseases.