Novel Thienopyrimidine Derivatives Containing 1,2,4-triazoles and 1,3,4-oxadiazoles as Potent Antimicrobial ActivityNagaraju Kerru, Triloknadh Settypalli, Harikrishana Nallapaneni and Venkata Rao Chunduri*
Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India
- *Corresponding Author:
- Venkata Rao Chunduri
Department of Chemistry, Sri Venkateswara University
Tirupati 517502, Andhra Pradesh, India
E-mail: [email protected]
Received date: July 31, 2014; Accepted date: August 27, 2014; Published date: August 30, 2014
Citation: Kerru N, Settypalli T, Nallapaneni H, Chunduri VR (2014) Novel Thienopyrimidine Derivatives Containing 1,2,4-triazoles and 1,3,4-oxadiazoles as Potent Antimicrobial Activity. Med chem 4:623-629. doi:10.4172/2161-0444.1000204
Copyright: © 2014 Kerru N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A series of thienopyrimidine oxadiazolederivatives (5a-l) were synthesized by cyclic condensation of substituted aroylhydrazides with triazole of carboxylic acid (4a-c). The synthesized compounds were characterized on the basis of their spectral (IR, 1H and 13C NMR) data and screened for antimicrobial activity where compounds 5b and 5d showed significant activity.