alexa Novel Thienopyrimidine Derivatives Containing 1,2,4-tri
ISSN: 2161-0444

Medicinal Chemistry
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Research Article

Novel Thienopyrimidine Derivatives Containing 1,2,4-triazoles and 1,3,4-oxadiazoles as Potent Antimicrobial Activity

Nagaraju Kerru, Triloknadh Settypalli, Harikrishana Nallapaneni and Venkata Rao Chunduri*

Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India

*Corresponding Author:
Venkata Rao Chunduri
Department of Chemistry, Sri Venkateswara University
Tirupati 517502, Andhra Pradesh, India
Tel: +91-877-2289303
Fax: +91-877-2249532
E-mail: [email protected]

Received date: July 31, 2014; Accepted date: August 27, 2014; Published date: August 30, 2014

Citation: Kerru N, Settypalli T, Nallapaneni H, Chunduri VR (2014) Novel Thienopyrimidine Derivatives Containing 1,2,4-triazoles and 1,3,4-oxadiazoles as Potent Antimicrobial Activity. Med chem 4:623-629. doi:10.4172/2161-0444.1000204

Copyright: © 2014 Kerru N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



A series of thienopyrimidine oxadiazolederivatives (5a-l) were synthesized by cyclic condensation of substituted aroylhydrazides with triazole of carboxylic acid (4a-c). The synthesized compounds were characterized on the basis of their spectral (IR, 1H and 13C NMR) data and screened for antimicrobial activity where compounds 5b and 5d showed significant activity.


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