NSAIDs; Safety and Risk Assessment in CVS Events, Comparisons and Facts
- *Corresponding Author:
- Safila Naveed
Faculty of Pharmacy, Jinnah University for Women
E-mail: [email protected]
Received Date: November 25, 2015 Accepted Date: January 27, 2016 Published Date: February 04, 2016
Citation: Hasnain H, Ali H, Tariq A, Zafar F, Naveed S (2016) NSAIDs; Safety and Risk Assessment in CVS Events, Comparisons and Facts. J Bioequiv Availab 8:084-088. doi:10.4172/jbb.1000273
Copyright: © 2016 Hasnain H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Products of Non-steroidal anti-inflammatory drugs (NSAIDs) are principally and most widely utilized due to their multipurpose actions, i.e., analgesic anti pyretic and anti-inflammatory effect. Beside their therapeutic effect their toxic effect based on their selectivity of cyclooxygenase (COX) enzyme. While cardiovascular toxicities associated with NSAIDs are mainly related with COX-2 selective inhibitor and primarily dependent on their dose time and duration. Variability in therapeutic response and susceptibility to toxicity is well recognized and can be manageable if considerable precautions implement.