alexa Nutraceutical Properties and Safety Evaluation of Fruits and Arrope of Geoffroea decorticans (Chañar)
ISSN: 2155-9600

Journal of Nutrition & Food Sciences
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Nutraceutical Properties and Safety Evaluation of Fruits and Arrope of Geoffroea decorticans (Chañar)

Reynoso MA1*, Sánchez Riera A1 and Vera NR2

1Cátedra de Farmacodinamia. Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, 4000, Tucumán, Argentina

2Cátedera de Farmacoquímica. Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, 4000, Tucumán, Argentina

*Corresponding Author:
Reynoso MA
Cátedra de Farmacodinamia. Facultad de Bioquímica
Química y Farmacia, Universidad Nacional de Tucumán
Ayacucho 471, 4000, Tucumán, Argentina
Tel: 54 381 424-7752
Fax: 54 0381 4293071
E-mail: mareynosofbqf@hotmail.com

Received Date: March 01, 2016 Accepted Date: March 25, 2016 Published Date: March 31, 2016

Citation: Adrián RM, Alicia SR, Roxana VN (2016) Nutraceutical Properties and Safety Evaluation of Fruits and Arrope of Geoffroea decorticans (Chañar). J Nutr Food Sci 6:485. doi: 10.4172/2155-9600.1000485

Copyright: © 2016 Reynoso MA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Context: Geoffroea decorticans (chañar) fruits and its derivate product (arrope) have been traditionally used as food and in folk medicine for the treatment of a wide variety of diseases including bronchopulmonary disorder.
Objective: The objective of this study is to evaluate the antitussive, expectorant and anti-inflammatory effects and safety of aqueous extract (AE) and arrope (Ar) of chañar.
Materials and methods: The anti-inflammatory activity of AE and Ar was evaluated through carrageenan induced edema and cotton pellet-induced granuloma formation in rats. The antitussive activity was evaluated using model against ammonia induced cough in rats. The expectorant activity was evaluated by volume of phenol red in rat’s tracheas. The tested doses of extracts were of 250, 500 and 1000 mg/kg, (p.o.). For the safety evaluation of AE and Ar, was conducted the subchronic toxicity test in rats (1 g/kg and 2 g/kg, p.o.).
Results: The results showed that AE (1000 mg/Kg) significantly reduced the edema (100%) induced by carrageenan 3 h post-dosing and granuloma formation (47.76%) induced by cotton pellets. In the ammonia liquor induced cough and the amount of phenol red secretion, AE and Ar of chañar (1000 mg/kg) significantly enhanced the latent period of cough, inhibited the cough frequency and significantly enhance tracheal phenol red compared with that negative control. The result of toxicity assays suggested that AE and Ar did not induce or cause any damage to the liver and kidney of the rats and can be considered nontoxic for these animals at tested doses.
Discussion and conclusion: This study has shown that the AE and Ar possess antitussive and expectorant significant effect. Also AE possess significant anti-inflammatory effects, both extracts were nontoxic. These findings seem to justify use of the plant in traditional medicine and are proposed, the chañar fruits as an excellent nutraceutical.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords