alexa Occurrence of Metachronous Multiple Malignancies. Revie
ISSN: 2471-8556

Oncology & Cancer Case Reports
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Case Report

Occurrence of Metachronous Multiple Malignancies. Review of the Literature: Case of Three Patients

Falkenstern Ge RF1*, Kimmich M1, Wohlleber M1, Bode-Erdmann S2, Hüttl K2, Grabner A2, Friedel G3, Ott G2 and Kohlhäufl M1

1Division of Pulmonology Center for Pulmonology and Thoracic Surgery, Teaching Hospital of the University of Tuebingen, Germany

2Department of Clinical Pathology, Teaching Hospital of the University of Tuebingen, Germany

3Division of Thoracic Surgery, Center for Pulmonology and Thoracic Surgery, Teaching Hospital of the University of Tuebingen, Germany

Corresponding Author:
Falkenstern Ge RF
Division of Pulmonology
Klinik Schillerhoehe
Center for Pulmonology and Thoracic Surgery
Teaching Hospital of the University of Tuebingen
Solitude Str. 18, 70839 Stuttgart- Gerlingen
Germany
Tel: 07156-2030
E-mail: [email protected]

Received March 30, 2016; Accepted April 29, 2016; Published May 02, 2016

Citation: Falkenstern Ge RF, Kimmich M, Wohlleber M, Bode-Erdmann S, Hüttl K, et al. (2016) Occurrence of Metachronous Multiple Malignancies. Review of the Literature: Case of Three Patients. Oncol Cancer Case Rep 2:113. doi:10.4172/2471-8556.1000113

Copyright: © 2016 Falkenstern Ge GF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

We report the rare occurrence of multiple metachronous malignancies in three patients within different time frames from 18 months, 7 years and up to 25 years, respectively. Multiple primary malignant neoplasias (MPMN) are extremely rare. The key risk factors may be smoking and family history. While numerous studies have been published on the development of secondary malignancies following a first primary, the literature contains only few reports of patients with multiple metachrounous malignancies.

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