alexa Old-for-Old Age Matching in Living Donor Kidney Transpl
ISSN: 2161-0991

Journal of Transplantation Technologies & Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Old-for-Old Age Matching in Living Donor Kidney Transplantation: A Single-Center Experience

Takuzo Fujiwara1*, Shinichiro Tanaka1, Kei Namba1, Haruchika Yamamoto1, Shoma Teruta1, Nozomi Morikawa1, Shimpei Tsudaka1 and Hiroaki Matsuda2

1Department of Surgery, National Hospital Organization Okayama Medical Center, Okayama, Japan

2Department of Surgery, Saiwaicho Memorial Hospital, Okayama, Japan

*Corresponding Author:
Takuzo Fujiwara
Department of Surgery
National Hospital Organization Okayama Medical Center
1711-1 Tamasu, Kita-ku, Okayama 701-1192, Japan
Tel: +81-86-294-9911
Fax: +81-86-294-9255
E-mail: [email protected]

Received Date: September 19, 2014; Accepted Date: October 21, 2014; Published Date: October 23, 2014

Citation: Fujiwara T, Tanaka S, Namba K, Yamamoto H, Teruta S, et al. (2014) Old-for-Old Age Matching in Living Donor Kidney Transplantation: A Single-Center Experience. J Transplant Technol Res 4: 141. doi: 10.4172/2161-0991.1000141

Copyright: © 2014 Fujiwara T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

The impact of donor age, especially from older donors (≥ 60 years), on recipient outcomes in living donor kidney transplantation were retrospectively evaluated in 181 consecutive primary kidney transplant recipients. Patients were categorized according to donor age: age ≤ 39 (n=15), 40‒49 (n=28), 50‒59 (n=71), and ≥ 60 years (n=67). Cox proportional hazard multivariate analysis was used to calculate the relative risk of patient and graft survival. Cox analysis showed that donor age, as a continuous variable, was not a risk factor for patient or graft survival. Deathuncensored (65.4%) and censored (73.1%) graft survival rates in the oldest donor group were lowest, although the differences did not reach statistical significance (p=0.086 and 0.127, respectively). Mean estimated glomerular filtration rates one year after transplantation in these 4 groups were 63.1 ± 13.9, 60.4 ± 18.5, 49.2 ± 15.4 and 42.6 ± 11.4 ml/ min/1.73 m2, respectively (p < 0.001). Subdivision by age of recipients of kidney donors ≥ 60 years into those aged, ≤ 39, (n=31), 40-59, (n=25) and ≥ 60 (n=11) years, showed optimal results in old for old combination transplants. The death-uncensored graft survival rates in the 3 subgroups were 64.5%, 76.0% and 90.9%, respectively (p=0.869), whereas their mean estimated glomerular filtration rates 1 year after transplantation were 40.7 ± 7.4, 41.0 ± 10.7 and 51.4 ± 14.3 ml/min/1.73 m2, respectively (p=0.025). Age-matching may be beneficial when performing living donor kidney transplantation from older donors.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords