Journal of Cytology & Histology
Open Access

Case Report

Oncocytic Papillary Cystadenoma with Tyrosine-rich Crystalloids in the Parotid: Case Report with Cytology and Histology Correlation and Literature Review

Jamal Musayev^1*, Binnur Önal², Chingiz Rahimov³, Adalat Hasanov¹, Ismayil Farzaliyev³ and Mahira Nazirova⁴

¹Department of Pathology, Azerbaijan Medical University, Baku, Azerbaijan

²Department of Pathology and Cytology, Ankara Diskapi Teaching and Research Hospital, Ankara, Turkey

³Department of Oral and Maxillofacial Surgery, Azerbaijan Medical University, Baku, Azerbaijan

⁴Unification of Forensic Medical Expertise and Pathological Anatomy, Baku, Azerbaijan

*Corresponding Author:

Jamal Musayev
Department of Pathology
Azerbaijan Medical University
Baku, Azerbaijan
Tel: 00994503393684
E-mail: [email protected]

Received Date: July 26, 2015 Accepted Date: August 27, 2015 Published Date: August 29, 2015

Citation: Musayev J, Onal B, Rahimov C, Hasanov A, Farzaliyev I, et al. (2015) Oncocytic Papillary Cystadenoma with Tyrosine-rich Crystalloids in the Parotid: Case Report with Cytology and Histology Correlation and Literature Review. J Cytol Histol 6:361. doi:10.4172/2157-7099.1000361

Copyright: © 2015 Musayev J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Oncocytic papillary cystadenomas are rare benign salivary gland neoplasms. Minor salivary glands are frequent localization for this neoplasm. We report a case of oncocytic papillary cystadenoma of the parotid gland, occurring in a 53-year-old male as a slowly growing, well defined cystic nodule of 1.5 cm in diameter. Fine needle aspiration (FNA) was performed by using 25-gauge needle by the (cyto) pathologist. Few small sheets of epithelial and oncocytic degenerative cells with extensive granular debris on the background were observed on FNA smears. Few tabular or petal form, non-birefringent crystalloids were noted in the background of scanty cellular specimens composed predominantly of oncocytic cells. On histopathology, unilocular cystic lesion with papillary structures lined by oncocytic cells and tyrosine-rich crystalloids within the lumen were identified. In conclusion, oncocytic papillary cystadenoma is uncommon benign tumor in the parotid gland and can be accompanied by tyrosine-rich crystalloids. It is useful to be familiar with the type of the crystalloid as they may help in differentiating benign and malignant lesions. To the best of authors' knowledge, this is the second reported case of oncocytic papillary cystadenoma with crystalloids with cyto-histo correlation.

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