alexa One Pot Synthesis, Antimicrobial and In Silico Molecular Docking Study of 1,3-Benzoxazole-5-Sulfonamide Derivatives
ISSN: 2161-0401

Organic Chemistry: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

One Pot Synthesis, Antimicrobial and In Silico Molecular Docking Study of 1,3-Benzoxazole-5-Sulfonamide Derivatives

Vinoda BM1, Bodke YD1*, Vinuth M1, Aruna Sindhe M1, Venkatesh T1 and Sandeep Telkar2

1Department of PG Studies and Research in Industrial Chemistry, Kuvempu University, Karnataka-577 451, India

2Department of PG Studies and Research in Biotechnology, Kuvempu University, Karnataka-577 451, India

*Corresponding Author:
Bodke YD
Department of PG Studies and Research in Industrial Chemistry
Kuvempu University
Karnataka-577 451, India
Tel: +918282256228
E-mail: [email protected]

Received date: April 01, 2016; Accepted date: April 11, 2016; Published date: April 18, 2016

Citation: Vinoda BM, Bodke YD, Vinuth M, Sindhe MA, Venkatesh T, et al. (2016) One Pot Synthesis, Antimicrobial and In Silico Molecular Docking Study of 1,3-Benzoxazole-5-Sulfonamide Derivatives. Organic Chem Curr Res 5: 163. doi:10.4172/2161-0401.1000163

Copyright: © 2016 Vinoda BM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



A series of 1,3-benzoxazole-5-sulfonamide derivatives have been synthesized via acetophenones, aldehydes and 2-sulfanyl-1,3-benzoxazole-5-sulfonamide using Fe(III)-montmorillonite (Fe(III)-mont) as catalyst. Catalyst is good Lewis acid and support to increase the yield of the final compounds. The structures of newly synthesized compounds were confirmed by FTIR, 1H NMR, 13C NMR and Mass spectroscopic methods. The antimicrobial potential of title compounds was tested against several bacterial and fungal strains. Some compounds exhibited comparable or better antimicrobial activity in comparison to the reference drugs Ciprofloxacin and Fluconozole. The selected compounds were also subjected for in silico molecular docking study.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version